Abstract
To evaluate the uncertainty of the determination of sibutramine content in health foods by liquid chromatography-tandem mass spectrometry. Methods according to BJS 201701 Determination of sibutramine in food,and the content of sibutramine in health foods was detected. According to the approach in measurement uncertainty and results indication(JJF 1059.1 2012), the uncertainty was analyzed, quantified and synthesized. When sibutramine content was 7.04 μg/g,the extended uncertainty was 0.197 μg/g (k=2) under the 95% confidence interval. The main influence factors of the uncertainties in the determination were standard curve fitting process.
Publication Date
4-28-2020
First Page
91
Last Page
94
DOI
10.13652/j.issn.1003-5788.2020.04.017
Recommended Citation
Sai-nan, WANG; Ying-chun, DENG; Tian-lan-xing, GAO; Meng-ke, REN; Hua-lin, WEI; Wen-li, ZHI; and Xu-guang, GUO
(2020)
"Uncertainty evaluation for determination of sibutramine in health foods by liquid chromatography-tandem mass spectrometry,"
Food and Machinery: Vol. 36:
Iss.
4, Article 17.
DOI: 10.13652/j.issn.1003-5788.2020.04.017
Available at:
https://www.ifoodmm.cn/journal/vol36/iss4/17
References
[1] 李铮,佟旭光.西布曲明的不良反应研究进展[J].首都医药,2011,18(14):42-43.
[2] 国家食品药品监督管理局.关于西布曲明的最新国际安全性信息:摘录[J].中国社区医师,2010,26(15):8.
[3] 魏艳红.关于盐酸西布曲明安全审查的早期报告[J].药品评价,2010,7(2):29.
[4] 钟凯.网络假劣药品泛滥小心中招[N].健康报,2017-07-21(004).
[5] 龙敏飞.多管齐下堵住“网红药”漏洞[N].中国商报,2018-06-12(P02).
[6] 郑毅,曾峰.曝上亿假减肥药黑幕:每粒成本几分钱[J].人民之友,2017(10):46-47.
[7] 杨娟,杨晓云,钟昕,等.测量不确定度在食品检验检测中的应用及研究进展[J].食品安全导刊,2019(18):93-95.
[8] 师源,郭家琪,朱天钧,等.氢化物发生原子荧光光谱法测定绿豆中砷的测量不确定度评定[J].分析仪器,2018(6):112-116.
[9] 倪育才.测量不确定度理解与应用(一):如何建立数学模型[J].中国计量,2004(7):72-74.[ZK)]
[10] 欧阳丽,汪辉,何翊,等.UPLC-MS/MS测定猪肝中五氯酚残留量的不确定度评定[J].食品与机械,2019,35(9):84-88.
[11] 卫星,李小红,董曼曼,等.LC-MS/MS法测定火锅食品中5种罂粟壳生物碱的不确定度评定[J].食品与机械,2019,35(8):77-82,154.
[12] 肖利龙,花锦.高效液相色谱法测定花生酱中黄曲霉毒素B1结果不确定度的评定[J].食品与机械,2018,34(3):79-81,150.
[13] 王赛楠.高效液相色谱法测定水果罐头中阿斯巴甜的不确定度评估[J].食品安全质量检测学报,2019,10(3):734-739.
[14] 黄坤,王会霞,范小龙,等.超高效液相色谱—串联质谱法测定炒货中纽甜含量的不确定度评定[J].食品与机械,2019,35(8):64-68,72.
[15] 程福安,章家岩,冯旭刚,等.基于灰色模型的蔬菜农药残留量不确定度评定[J].食品与机械,2019,35(7):98-102.