Study on the preparation of tetracyline magnetic molecularly imprinted biochar microspheres based on Pickering emulsion polymerization

Authors

MA Zhen-zhen, College of Food Science and Engineering, Qilu University of Technology 〔Shandong Academy of Sciences〕, Jinan, Shandong 250353 , China
HE Jin-xing, College of Food Science and Engineering, Qilu University of Technology 〔Shandong Academy of Sciences〕, Jinan, Shandong 250353 , China
ZHAO Tao, College of Food Science and Engineering, Qilu University of Technology 〔Shandong Academy of Sciences〕, Jinan, Shandong 250353 , China
ZHAO Xiao-lei, College of Food Science and Engineering, Qilu University of Technology 〔Shandong Academy of Sciences〕, Jinan, Shandong 250353 , China

Abstract

In this study, magnetic molecularly imprinted biochar microspheres for specific adsorption of tetracylines (TCs) were prepared by Pickering emulsion polymerization using tetracyline (TC) as template and Fe₃O₄ and biochar as co-stabilizers. The adsorption properties of the imprinted microspheres for TC were studied by adsorption kinetics test, adsorption isothermal test, and selectivity adsorption test, exhibiting the excellent specific adsorption for TC with imprinting factor of 3.97. Further more, the imprinted materials were used as adsorbents for extraction and purification of TCs in real samples, and the content of TCs were detected through high performance liquid chromatography (HPLC). Under the control of the optimum conditions, the established method showed a good linearity in the range from 5 μg/L to 160 μg/L with the precision of 1.23%~9.99%, limits of detection (LOD) of 1.42~1.58 μg/L, and high recoveries of 90.6%~103.4%. This indicated that the proposed method could be applied for the accurate analysis of TCs at trace level in food.

Publication Date

5-28-2020

First Page

70

Last Page

75,94

DOI

10.13652/j.issn.1003-5788.2020.05.013

Recommended Citation

Zhen-zhen, MA; Jin-xing, HE; Tao, ZHAO; and Xiao-lei, ZHAO (2020) "Study on the preparation of tetracyline magnetic molecularly imprinted biochar microspheres based on Pickering emulsion polymerization," Food and Machinery: Vol. 36: Iss. 5, Article 13.
DOI: 10.13652/j.issn.1003-5788.2020.05.013
Available at: https://www.ifoodmm.cn/journal/vol36/iss5/13

References

[1] DAGHRIR R,DROGUI P.Tetracycline antibiotics in the environment:A review[J].Environmental Chemistry Letters,2013,11(3):209-227.
[2] LIU Xi-qing,WANG Tao,WANG Wen-juan,et al.A tailored molecular imprinting ratiometric fluorescent sensor based on red/blue carbon dots for ultrasensitive tetracycline detection[J].Journal of Industrial and Engineering Chemistry,2019,72:100-106.
[3] SHAO Si-chen,HU Yong-you,CHENG Jian-hua,et al.Research progress on distribution,migration,transformation of antibiotics and antibiotic resistance genes(ARGs)in aquatic environment[J].Critical Reviews in Biotechnology,2018,38(8):1-14.
[4] LI Wen-qing,DRUCKER A M,CHO E,et al.Tetracycline use and risk of incident skin cancer:A prospective study[J].British Journal of Cancer,2018,118:294-298.
[5] XU Hui,MI Hong-yu,GUAN Ming-ming,et al.Residue analysis of tetracyclines in milk by HPLC coupled with hollow fiber membranes-based dynamic liquid-liquid micro-extraction[J].Food Chemistry,2017,232:198-202.
[6] YANG Ji,LIN Zheng-zhong,NUR A Z,et al.Detection of trace tetracycline in fish via synchronous fluorescence quenching with carbon quantum dots coated with molecularly imprinted silica[J].Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy,2018,190(1):450-456.
[7] CHEN Yan-ni,KONG De-zhao,LIU Li-qiang,et al.Development of an ELISA and immunochromatographic assay for tetracycline,oxytetracycline,and chlortetracycline residues in milk and honey based on the class-specific monoclonal antibody[J].Food Analytical Methods,2016,9(4):905-914.
[8] KURITTU J,LNNBERG S,VIRTA M,et al.A group-specific microbiological test for the detection of tetracycline residues in raw milk[J].Journal of Agricultural and Food Chemistry,2000,48(8):3 372-3 377.
[9] HUANG Yun-fei,YAN Xiao-chen,ZHAO Lian-hui,et al.An aptamer cocktail-based electrochemical aptasensor for direct capture and rapid detection of tetracycline in honey[J].Microchemical Journal,2019,150:104179.
[10] AHMED M B,ZHOU Jun-liang,NGO H H,et al.Competitive sorption affinity of sulfonamides and chloramphenicol antibiotics toward functionalized biochar for water and wastewater treatment[J].Bioresource Technology,2017,238:306-312.
[11] SHEN Qi-bin,WANG Zhao-yue,YU Qiao,et al.Removal of tetracycline from an aqueous solution using manganese dioxide modified biochar derived from Chinese herbal medicine residues[J].Environmental Research,2020,183:109195.
[12] CHANG Rui-hai,SOHI S P,JING Fan-qi,et al.A comparative study on biochar properties and Cd adsorption behavior under effects of ageing processes of leaching,acidification and oxidation[J].Environmental Pollution,2019,254:113123.
[13] SPELTINI A,SCALABRINI A,MARASCHI F,et al.Newest applications of molecularly imprinted polymers for extraction of contaminants from environmental and food matrices:A review[J].AnalyticaChimica Acta,2017,974:1-26.
[14] BINKS B P.Particles as surfactants-similarities and differences[J].Current Opinion in Colloid & Interface Science,2002,7(1):21-41.
[15] AVEYARD R,BINKS B P,CLINT J H.Emulsionsstabilised solely by colloidal particles[J].Advances in Colloid and Interface Science,2003,100/101/102:503-546.
[16] FENG Meng-xiao,WANG Geng-nan,YANG Kun,et al.Molecularly imprinted polymer-high performance liquid chromatography for the determination of tetracycline drugs in animal derived foods[J].Food Control,2016,69:171-176.
[17] GRANDE-MARTÍNEZÁ,MORENO-GONZÁLEZ D,ARREBOLA-LIÉBANAS F J,et al.Optimization of a modified QuEChERS method for the determination of tetracyclines in fish muscle by UHPLC-MS/MS[J].Journal of Pharmaceutical and Biomedical Analysis,2018,155:27-32.