Advances in research of CFTR inhibitors extracted from foods and herbal plants

Authors

LUAN Jian, School of Life Sciences, Liaoning Normal University, Dalian, Liaoning 116029, China; School of Life Sciences, Jilin Normal University, Siping, Jilin 136000, China
YANG Hong, School of Life Sciences, Liaoning Normal University, Dalian, Liaoning 116029, China

Abstract

CFTR chloride channel is the molecular drug target for the treatment of secretory diarrhea. Screening CFTR inhibitors is the most important and basic part of anti-diarrheal drug development. The natural products are diversified both in the structure and the biological activity. In the discovery of drugs and leading compounds, natural products play a key role and become the main source of drug development. Natural products from foods and herbal plants are usually safe for low or no toxicity and side-effect in clinic. CFTR inhibitors which source of foods and traditional Chinese medicines are important of study and treatment of CFTR related diseases, as well as providing a basis for the modern drug discovery in the natural product resources.

Publication Date

12-28-2015

First Page

219

Last Page

223

DOI

10.13652/j.issn.1003-5788.2015.06.052

Recommended Citation

Jian, LUAN and Hong, YANG (2015) "Advances in research of CFTR inhibitors extracted from foods and herbal plants," Food and Machinery: Vol. 31: Iss. 6, Article 52.
DOI: 10.13652/j.issn.1003-5788.2015.06.052
Available at: https://www.ifoodmm.cn/journal/vol31/iss6/52

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