On-line determination of emergency pollution of 3-nitropropionic acid in drinking water by flow injection chemiluminescence

Authors

ZHANG Xuhui, Department of Food Science and Engineering, Jinan University, Guangzhou, Guangdong 510632, China
TANG Shuze, Department of Food Science and Engineering, Jinan University, Guangzhou, Guangdong 510632, China
DENG Xiaoling, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong 510300, China
ZHU Yao, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong 510300, China
WU Shizheng, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong 510300, China

Abstract

On the basis of inhibition of chemiluminescence reaction of luminol and potassium permanganate in sodium hydroxide medium by 3-nitropropionic acid, a novel flow-injection chemiluminescence method for determination of 3-nitropropionic acid in drinking water was developed. A linear range for 3-nitropropionic acid determination was 1～150 mg/L. The detection limit of 3-nitropropionic acid was 0.28 mg/L and relative standard deviation (RSD) was 1.9%, with the recovery of 76.5%～93.8%. This online determination system showed a good accuracy and selectivity and has great potential application in rapid detection and alarm of emergency pollution of 3-nitropropionic acid in drinking water.

Publication Date

11-28-2016

First Page

45

Last Page

49

DOI

10.13652/j.issn.1003-5788.2016.11.010

Recommended Citation

Xuhui, ZHANG; Shuze, TANG; Xiaoling, DENG; Yao, ZHU; and Shizheng, WU (2016) "On-line determination of emergency pollution of 3-nitropropionic acid in drinking water by flow injection chemiluminescence," Food and Machinery: Vol. 32: Iss. 11, Article 10.
DOI: 10.13652/j.issn.1003-5788.2016.11.010
Available at: https://www.ifoodmm.cn/journal/vol32/iss11/10

References

[1] 陈晓明, 胡文娟, 陈君石. 天然毒素3-硝基丙酸的研究现状[J]. 国外医学: 卫生学分册, 1988, 17(3): 158-161.
[2] JAMES L F, HARTLEY W J, WILLIAMS M C, et al. Field and experimental studies in cattle and sheep poisoned by nitro-bearing Astragalus or their toxins[J]. Am. J. Vet. Res, 1980(41): 377-382.
[3] FU Y, HE F, ZHANG S, et al. Consistent striatal damage in rats induced by 3-nitropropionic acid and cultures of Arthrinium fungus[J]. Neurotoxicology and Teratology, 1995, 17(4): 413-418.
[4] LUDOLPH A C, HE F, SPENCER P S, et al. 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin[J]. Can. J. Neurol. Sci, 1991(18): 492-498.
[5] GUSTINE D L. Aliphatic nitro compounds in crown vetch: a review[J]. Crop Science, 1979(19): 197-203.
[6] 刘兴玠, 李秀芳, 孙艳洁, 等. 变质甘蔗中毒的预防研究-Ⅰ: 流行病学的调查分析[J]. 卫生研究, 1993, 22(1): 31-33.
[7] JOHNSON J R, ROBINSON B L, ALI S F, et al. Dopamine toxicity following long term exposure to low doses of 3-nitropropionic acid (3-NPA) in rats[J]. Toxicology Letters, 2000(116): 113-118.
[8] BELL M E. Toxicology of karaka kernel, karakin, and 3-nitropropionic acid[J]. New Zealand J. Sci., 1974(17): 327-334 .
[9] 刘兴玠, 罗雪云, 胡霞, 等. 产毒节菱孢培养物对动物的毒性研究[J]. 卫生研究, 1987, 16(5): 26-29.
[10] 赵秀勉, 徐玮, 张海红. 变质甘蔗中毒病原菌节菱孢霉菌及其毒素国内研究进展[J]. 河北医学院学报, 1995, 16(3): 183-184.
[11] MOSKOWITZ G J, CAYLE T. A method for the detection of 3-nitropropionic acid in crude biological extracts[J]. Cereal Chemistry, 1974(51): 96-105.
[12] 胡文娟, 王玉华, 陈晓明, 等. 甘蔗及甘蔗汁中3-硝基丙酸的薄层色谱测定法[J]. 卫生研究, 1988, 17(5): 39-42.
[13] 解娜, 丁晓静, 张晶, 等. 毛细管电泳法测定甘蔗中3-硝基丙酸[J]. 食品安全质量检测学报, 2013(3): 710-714.
[14] 邵国健, 韩建康, 吴丹青. 免试剂离子色谱法测定变质甘蔗中3-硝基丙酸[J]. 中国卫生检验杂志, 2012, 4(3): 711-712.
[15] 刘勇, 吴南, 吴永宁, 等. 3-硝基丙酸的气相色谱-热能检定器测定法及其在大鼠体内的毒物代谢动力学研究[J]. 卫生研究, 1993, 22(1): 35-38.
[16] MUIR A D, MAJAK W. Quantitative determination of 3-nitropropionic acid and 3-nitropropanol in plasma by HPLC[J]. Toxicology Letters, 1984(20): 133-136.
[17] 江涛, 张庆林, 罗雪云. 3-硝基丙酸的高效液相色谱分析[J]. 卫生研究, 1999, 28(5): 300-303.
[18] 李兵, 吴国华, 刘伟, 等. 固相萃取-超高效液相色谱串联质谱法检测甘蔗中3-硝基丙酸的方法研究[J]. 中国食品卫生杂志, 2012, 24(2): 127-132.
[19] IRANIFAM M. Flow analysis and chemiluminescence: An update advances in flow-chemiluminescence analysis[M]. [S. l.]: Lambert Academic Publishing, 2011: 163-166.
[20] 朱曜, 刘爽, 张旭辉, 等. 饮用水中秋水仙碱含量预警的在线监测方法[J]. 湖南农业大学学报, 2015, 41(5): 538-543.
[21] 刘爽, 马强, 朱曜, 等. 鲁米诺-铁氰化钾流动注射化学发光法对饮用水中桔霉素的快速预警[J]. 食品工业, 2014, 35(8): 274-277.
[22] 马强, 朱定波, 杨杏芳, 等. 鲁米诺-铁氰化钾流动注射化学发光体系测定饮用水中棒曲霉素[J]. 食品工业科技, 2013, 34(15): 306-323.
[23] 朱定波, 马强, 燕廷, 等. 鲁米诺-铁氰化钾流动注射化学发光体系测定饮用水中ɑ-茄碱[J]. 食品工业科技, 2012, 33(22): 84-86.
[24] 翟倩, 李晓璐, 俞宏松, 等. 流动注射化学发光法测定注射用比阿培南[J]. 国际药学研究杂志, 2015, 42(5): 642-645.
[25] KHATAEE A R, HASANZADEH A, IRANIFAM M, et al. CuO nanosheets-enhanced flow-injection chemiluminescence system for determination of vancomycin in water, pharmaceutical and human serum[J]. Biomolecular Spectroscopy, 2014(122): 737-743.
[26] 张璐, 乐爱山, 郑玲, 等. 固相萃取/超高效液相色谱-电喷雾串联质谱法检测酶制剂中3-硝基丙酸[J]. 分析测试学报, 2013, 32(6): 747-752.
[27] 李兵, 吴国华, 刘伟, 等. 固相萃取-超高效液相色谱串联质谱法检测甘蔗中3-硝基丙酸的方法研究[J]. 中国食品卫生杂志, 2012, 24(2): 127-132.