Simultaneous determination of suIfonamides and quinIones infish by UPLC-Q/Orbitrap HRMS

Authors

YANG Luqi, Guangdong Pharmaceutical University, Zhongshan, Guangdong 528458, China; Zhongshan Entry-Exit Inspection and Quarantine Bureau, Zhongshan, Guangdong 528400, China
LI Rong, Zhongshan Entry-Exit Inspection and Quarantine Bureau, Zhongshan, Guangdong 528400, China
GAO Yongqing, Guangdong Pharmaceutical University, Zhongshan, Guangdong 528458, China
ZHANG Pengjie, Zhongshan Entry-Exit Inspection and Quarantine Bureau, Zhongshan, Guangdong 528400, China
ZHANG Pengyun, Guangdong Pharmaceutical University, Zhongshan, Guangdong 528458, China; Zhongshan Entry-Exit Inspection and Quarantine Bureau, Zhongshan, Guangdong 528400, China

Abstract

An Ultra-High Performance Liquid Chromatography-Quadrupole/Electrostatic Field Orbitrap High-resolution Mass Spectrometry method （UPLC-Q-Orbitrap HRMS）has been developed for the determinations of the drug residues of 21 SAs and 12 QNs in aquatic products.The sample was extracted by acetonitrile, cleaned up by acetonitrile saturated normal hexane and quantified in internal standard method.The results showed that 33 products presented a good linear relation in the range of 0.1～100 ng/mL. r²＞0.996. The limits for qualitative detection was 2 μg/kg. The average recoveries at three spike levels ranged were 54.3%～120.4%, with RSDs ranging 1.7%～11.9%. The developed method was easy operation high sensitivity, which can meet the requirements of daily inspection.

Publication Date

8-28-2017

First Page

38

Last Page

43

DOI

10.13652/j.issn.1003-5788.2017.08.010

Recommended Citation

Luqi, YANG; Rong, LI; Yongqing, GAO; Pengjie, ZHANG; and Pengyun, ZHANG (2017) "Simultaneous determination of suIfonamides and quinIones infish by UPLC-Q/Orbitrap HRMS," Food and Machinery: Vol. 33: Iss. 8, Article 10.
DOI: 10.13652/j.issn.1003-5788.2017.08.010
Available at: https://www.ifoodmm.cn/journal/vol33/iss8/10

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