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Abstract

The flavonoids from stems and leaves of Physalis alkekengi ( PSF ) were refined by macroporous adsorption resin, and their antioxidant activities were evaluated in vitro and in vivo. The PSF were obtained using with AB-8 macroporous adsorption resin washed by 70% ethanol, and the purity was 39.16%. After refining, the scavenging activities of PSF on NO-2·and ABTS+· were 81.36% and 91.49%. The anti-oxidative capability in linoleic acid lipid overoxidation system was 85.26%. The refined PSF not only significantly increased thymus index and spleen index(P<0.05), but also increased the activity of T-AOC, GSH-Px and SOD in serum(P<0.05) and decreased the content of MDA in serum(P<0.01). The refined PSF showed strong antioxidant activity in vitro and in vivo.

Publication Date

10-28-2018

First Page

158

Last Page

162

DOI

10.13652/j.issn.1003-5788.2018.10.032

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