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Abstract

Four substances (theanine, gamma-aminobutyric acid, beta-carotene and grape seed extract) were added into the chocolate and the improvement effect of these substances on asthenopia of 102 test persons were studied by questionnaire, vision test, attention test, memory test and brain wave test for 30 days. The questionnaire results showed that the total and single score (ocular discomfort score and general malaise score) of sample group were lower than the score before eating the sample chocolate, which is indicated that the asthenopia was improved by eating the sample chocolate, for example, the score of blurred vision was decreased by 0.21 and the score of subjective memory loss was decreased by 0.46 after eating the sample chocolate for 7 days. Attention test and memory test results showed that the attention and memory of sample group were improved significantly with cumulative effects and short-term effects, respectively. And the Sult square time and brain age were decreased by 5.09 s and 2.49, respectively. In the brain wave test, the alpha wave power value, the percentage of the alpha wave power value spectrum and the percentage ratio of the α/β wave power value spectrum which reflect the relaxation degree of the brain in the Lead P4 and Lead O2 of the sample group were increased, and the Lead P4 increased 7.69, 0.04 and 0.50, the Lead O2 increased by 9.90, 0.04 and 0.73, respectively. Therefore, a chocolate product containing theanine, gamma-aminobutyric acid, beta-carotene and grape seed extract plays a mitigation role on asthenopia.

Publication Date

10-28-2018

First Page

19

Last Page

25,74

DOI

10.13652/j.issn.1003-5788.2018.10.004

References

[1] 宿蕾艳, 庄曾渊. 视疲劳病因机制及防治的研究进展[J]. 中国中医眼科杂志, 2010, 20(3): 183-185.
[2] THORUD H M S, HELLAND M, AARS A, et al. Eye-related pain induced by visually demanding computer work[J]. Optometry and Vision Science, 2012, 89(4): E452-E464.
[3] 王家琦, 翟玥, 刘泽豫, 等. 大学生电子产品使用与视疲劳发生的相关性分析[J]. 眼科新进展, 2018, 38(1): 65-68.
[4] YE Zhao-jia, ABE Y, KUSANO Y, et al. The influence of visual display terminal use on the physical and mental conditions of administrative staff in Japan[J]. Journal of Physiological Anthropology, 2007, 26(2): 69-73.
[5] PARK C Y, GU N, LIM C Y, et al. The effect ofVaccinium uliginosum extract on tablet computer-induced asthenopia: randomized placebo-controlled study[J]. BMC Complementary and Alternative Medicine, 2016, 16(1): 296.
[6] 吴盛, 吴至凤. 视疲劳研究概述[J]. 赣南医学院学报, 2007, 27(3): 480-482.
[7] MOCCI F, SERRA A, CORRIAS G A. Psychological factors and visual fatigue in working with video display terminals[J]. Occupational and Environmental Medicine, 2001, 58(4): 267-271.
[8] YE Zhao-jia, HONDA S, ABE Y, et al. Influence of work duration or physical symptoms on mental health among Japanese visual display terminal users[J]. Industrial Health, 2007, 45(2): 328-333.
[9] TIPPIN J, SPARKS J D, RIZZO M. Visual vigilance in drivers with obstructive sleepapnea[J]. Journal of Psychosomatic Research, 2009, 67(2): 143-151.
[10] INSANA S P, MONTGOMERY-DOWNS H E. Maternal postpartum sleepiness and fatigue: associations with objectively measured sleep variables[J]. J Psychosom Res, 2010, 69(5): 467-473.
[11] 李志英, 王燕, 叶笑妮, 等. 视疲劳的病因证治及其调养摄要[J]. 中医药学刊, 2003, 21(10): 1 632-1 633.
[12] 马越, 张超, 王丹, 等. 花青素饮料缓解人体视疲劳作用研究[J]. 食品科技, 2015, 40(2): 104-107.
[13] 金鑫, 臧茜茜, 葛亚中, 等. 缓解视疲劳功能食品及其功效成分研究进展[J]. 食品科学, 2015, 36(3): 258-264.
[14] 路秋丽. β-胡萝卜素的研究进展[J]. 徐州医学院学报, 2006, 26(6): 590-592.
[15] 陈子畅, 樊芯, 李晓燕, 等. 维生素A对光损伤小鼠视网膜功能和结构的保护作用[J]. 宁夏医科大学学报, 2016, 38(7): 750-754.
[16] 王黎颖, 杨国兰, 田甜, 等. 盐藻粉和蓝莓提取物的毒理学安全性评价[J]. 毒理学杂志, 2018, 32(3): 252-255.
[17] 何玉莲. 越橘叶黄素酯β-胡萝卜素软胶囊生产工艺及其质量控制点[J]. 食品安全质量检测学报, 2016, 7(12): 4 821-4 825.
[18] 王丽娟, 张慧, 张立冬, 等. β-胡萝卜素的研究进展及应用[J]. 中国食品添加剂, 2013(S1): 148-152.
[19] 邓耀, 杨立亭, 廖国周. 葡萄籽提取物中原花青素含量测定[J]. 中国食品工业, 2016(2): 56-58.
[20] 隋晓春, 程显好, 张友军, 等. 一种抗辐射危害和缓解视疲劳保健食品的研制[J]. 食品与药品, 2007(11): 19-21.
[21] 程传兴, 刘晓飞, 王薇. γ-氨基丁酸的生理功能及制备方法[J]. 哈尔滨商业大学学报: 自然科学版, 2017(6): 693-697.
[22] 吕毅, 郭雯飞, 倪捷儿, 等. 茶氨酸的生理作用及合成[J]. 茶叶科学, 2003, 23(1): 1-5.
[23] 石亚亚, 贾尚智, 闵彩云. 茶氨酸保健功能研究进展[J]. 生物资源, 2010, 32(1): 52-56.
[24] 丁一, 艾华. γ-氨基丁酸与人体健康的关系[J]. 中国临床保健杂志, 2012, 15(1): 100-103.
[25] DODD F L, KENNEDY D O, RIBY L M, et al. A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood[J]. Psychopharmacology, 2015, 232(14): 2 563-2 576.
[26] HIGASHIYAMA A, HTAY H H, OZEKI M, et al. Effects of l-theanine on attention and reaction time response[J]. Journal of Functional Foods, 2011, 3(3): 171-178.
[27] 堀江典子, 菅美奈子, 金武祚. GABA(γ-氨基丁酸)的功能性[J]. 中国食品添加剂, 2010(6): 169-173.
[28] 中华医学会眼科学分会眼视光学组. 视疲劳诊疗专家共识(2014年)[J]. 中华眼视光学与视觉科学杂志, 2014(7): 385-387.
[29] 赵丹, 王朝旭. 茶氨酸的国内外研究现状[J]. 食品科学, 2002, 23(5): 145-147.
[30] 林伟东, 孙威江, 郭义红, 等. 茶叶中茶氨酸的研究与利用[J]. 食品研究与开发, 2016(20): 201-206.
[31] 邓乾春, 黄凤洪, 黄庆德, 等. 亚麻籽油软胶囊缓解视疲劳作用[J]. 食品研究与开发, 2011, 32(1): 118-122.
[32] 朱松, 王洪新. 茶氨酸生理功能及其在食品中应用[J]. 粮食与油脂, 2005(1): 44-46.
[33] 任晓亮. 薰衣草精油嗅吸对人体脑电波的影响[D]. 上海: 上海交通大学, 2012: 28-32.

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