Studies on curcumin and CFTR: refutation and recognition

Authors

LUAN Jian, College of Life Science, Jilin Normal University, Jilin Key Laboratory of Plant Resources Science and Green Production,Siping, Jilin 136000, China
CAO Huanhuan, Chaoyang Quality Inspection and Testing Center, Chaoyang, Liaoning 122000, China
ZHOU Xiaofu, College of Life Science, Jilin Normal University, Jilin Key Laboratory of Plant Resources Science and Green Production,Siping, Jilin 136000, China

Abstract

The research progress of curcumin stimulates mutant CFTR chloride channel since 2004 is summarizes in this review, and the process from discovery to refutation, from resistance to recognition of this theory are also discussed. Scientists prove that curcumin is a natural molecular activator of CFTR chloride channel, and plays an important role in the treatment of cystic fibrosis and the drug development, according the investigation of the experiment methods, mechanisms and pharmacokinetics. This review reveals the potential problems such as safe dose, and aims to provide references for cystic fibrosis drug research and development.

Publication Date

12-28-2018

First Page

141

Last Page

146

DOI

10.13652/j.issn.1003-5788.2018.12.029

Recommended Citation

Jian, LUAN; Huanhuan, CAO; and Xiaofu, ZHOU (2018) "Studies on curcumin and CFTR: refutation and recognition," Food and Machinery: Vol. 34: Iss. 12, Article 29.
DOI: 10.13652/j.issn.1003-5788.2018.12.029
Available at: https://www.ifoodmm.cn/journal/vol34/iss12/29

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