Abstract
The 13 nm gold nanoparticles were synthesized and were modified with Bisphenol A(BPA) aptamer. The oil-solubility Up-conversion nanoparticles (UCNPs) were modified with polyacrylic acid (PAA) to form water-solubility UCNPs. Then water-solubility UCNPs were coated with the complementary DNA strand. Based these nanoparticles, a FRET aptasensor for BPA was successfully fabricated by using Up-conversion nanoparticles as energy donor and gold nanoparticles as energy acceptor. The results show that the detection system has a good linear relationship at 1×10-9～1×10-3 mol/L (R2=0.992 3), and the detection limit is as low as 1×10-10 mol/L. The method is proved to be of good practicability through the experiment of adding the standard of water and milk samples.
Publication Date
9-28-2018
First Page
83
Last Page
87
DOI
10.13652/j.issn.1003-5788.2018.09.017
Recommended Citation
Zhou, XU; Shizhen, LU; Maolong, CHEN; Yingyue, ZHU; Li, DING; and Yunhui, CHENG
(2018)
"Highly Sensitive Detection of Bisphenol A Based on FRET from Up-conversion Nanoparticles to Gold Nanoparticles,"
Food and Machinery: Vol. 34:
Iss.
9, Article 17.
DOI: 10.13652/j.issn.1003-5788.2018.09.017
Available at:
https://www.ifoodmm.cn/journal/vol34/iss9/17
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