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Authors

YAO Yijun, College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, Jiangsu210023, China; Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, Jiangsu 210023, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China
WANG Lifeng, College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, Jiangsu210023, China; Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, Jiangsu 210023, China
YIN Shi, College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, Jiangsu210023, China; Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, Jiangsu 210023, China
XU Feiran, College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, Jiangsu210023, China; Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, Jiangsu 210023, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China
SHI Jiayi, College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, Jiangsu210023, China; Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, Jiangsu 210023, China
JU Xingrong, College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, Jiangsu210023, China; Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, Jiangsu 210023, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China

Abstract

In this study, the crude rapeseed peptide was used as the research object. After treatment with powdered activated carbon, peptide solution was adsorbed onto DA201-C macroporous adsorption resin and then desorbed by ethanol to obtain rapeseed refined peptides (RP75). The basic composition, antithrombotic activity, anti-inflammatory activity and amino acid composition of rapeseed refined peptides (RP75) were also analyzed. The results showed that the optimum process for the refining of the DA201-C macroporous adsorption resin were peptide concentration 30 mg/mL, flow rate 3 BV/h, pH 4.5 and desorption concentration of the ethanol 75%. Peptide content was 74.94%, no glucosinolate or phytic acid was detected in RP75. On the other hand, RP75 contained rich amino acids and exhibited excellent bioactivities including anti-thrombotic and anti-inflammatory activities with IC50 values of 8.82 mg/mL and 0.80 mg/mL. These results indicated that RP75 could be used as a potential health promoting ingredient with functional activity.

Publication Date

1-28-2019

First Page

164

Last Page

169,212

DOI

10.13652/j.issn.1003-5788.2019.01.029

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