Abstract
Polysaccharide is one of the main bioactive compounds in these mushroom which had been generally studied to have the health-promoting properties of anti-oxidation, antitumor, anti-inflammatory, immunoregulation. With the heat wave of gut microbiome rising, how the edible mushroom polysaccharide affects human health through the gut microbiome has become the focus of attention. This review discussed the efficacy and structure of edible mushroom polysaccharides, the composition, distribution and function of human gut microbiome, and how the mushroom polysaccharides affect human health through regulating the gut microbiome. At the same time, preliminary suggestions for the follow-up study of edible mushroom polysaccharides were put forward in this review.
Publication Date
10-28-2019
First Page
145
Last Page
149
DOI
10.13652/j.issn.1003-5788.2019.10.029
Recommended Citation
Mengya, CHENG; Yalan, YANG; Qiao, YANG; Lulu, FENG; Rengui, HUANG; Lufei, ZHENG; and Jiali, REN
(2019)
"Effect of edible mushroom polysaccharide on human gut microbiome,"
Food and Machinery: Vol. 35:
Iss.
10, Article 29.
DOI: 10.13652/j.issn.1003-5788.2019.10.029
Available at:
https://www.ifoodmm.cn/journal/vol35/iss10/29
References
[1] 黄年来. 中国最有开发前景的主要药用真菌[J]. 食用菌, 2005, 27(1): 2-4.
[2] ROUPAS P, KEOGH J, NOAKES M, et al. The role of edible mushrooms in health: Evaluation of the evidence[J]. Journal of Functional Foods, 2012, 4(4): 687-709.
[3] 梁雪, 倪秀珍, 汉丽萍. 食药用真菌多糖生物活性的研究进展[J]. 长春师范大学学报, 2018(10): 82-85.
[4] WASSER S. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides[J]. Applied Microbiology and Biotechnology, 2002, 60(3): 258-274.
[5] BORCHERS A T, STERN J S, HACKMAN R M, et al. Mushrooms, tumors, and immunity[J]. Proceedings of the Society for Experimental Biology & Medicine, 1999, 221(4): 281-293.
[6] WASSER S P. Medicinal mushroom science: History, current status, future trends, and unsolved problems[J]. International Journal of Medicinal Mushrooms, 2010, 12(1): 1-16.
[7] 李六文, 赵刚. 药用真菌多糖抗肿瘤免疫生物活性研究进展[J]. 中华肿瘤防治杂志, 2015, 22(14): 1 156-1 160.
[8] LIU Li-qiao, LI Ming-zhu, YU Mu-lan, et al. Natural polysaccharides exhibit anti-tumor activity by targeting gut microbiota[J]. Int J Biol Macromol, 2019, 121(7): 43-51.
[9] NOWAK R, NOWACKA-JECHALKE N, JUDA M, et al. The preliminary study of prebiotic potential of Polish wild mushroom polysaccharides: The stimulation effect on Lactobacillus strains growth[J]. European Journal of Nutrition, 2017, 57(4): 1 511-1 521.
[10] MENDEL F. Mushroom polysaccharides: Chemistry and antiobesity, antidiabetes, anticancer, and antibiotic properties in cells, rodents, and humans[J]. Foods, 2016, 5(4): 80-120.
[11] TRAMONTANO M, ANDREJEV S, PRUTEANU M, et al. Nutritional preferences of human gut bacteria reveal their metabolic idiosyncrasies[J]. Nature Microbiology, 2018, 3: 514-522.
[12] JAYACHANDRAN M, CHEN Jia-li, CHUNG S S M, et al. A critical review on the impacts of β-glucans on gut microbiota and human health[J]. The Journal of nutritional biochemistry, 2018, 61: 101-110.
[13] AIDA F, SHUHAIMI M, YAZID M, et al. Mushroom as a potential source of prebiotics: A review[J]. Trends in Food Science & Technology, 2009, 20(11/12): 567-575.
[14] 王芳. 广西巴马长寿老人肠道菌群及其与膳食纤维多糖饮食关联性研究[D]. 南宁: 广西大学, 2015: 20-31.
[15] 齐翠娟. 肠道菌群在1型糖尿病患者的结构特征及潜在致病机制研究[D]. 北京: 北京协和医学院, 2016: 6-11.
[16] 罗月梅. 菊粉类果聚糖对肠道菌群影响的随机对照临床研究[D]. 广州: 南方医科大学, 2018.
[17] 方正. 通过16S rRNA序列分析探讨抑郁症与肠道菌群之间的相互联系[D]. 重庆: 重庆医科大学, 2016: 22-30.
[18] 王雪. 长根菇胞外多糖对肠道微生态的影响及其抗氧化作用的研究[D]. 泰安: 山东农业大学, 2015.
[19] 李晶. 主食变换对蒙古国志愿者肠道菌群结构及功能影响研究[D]. 呼和浩特: 内蒙古农业大学, 2017: 1-11.
[20] 吴欢. 遗传性肥胖儿童营养干预后肠道内优势菌的分离鉴定及生理功能的探究[D]. 上海: 上海交通大学, 2015.
[21] XU Xiao-fei, XU Ping-ping, MA Chuang-wah, et al. Gut microbiota, host health, and polysaccharides[J]. Biotechnol Adv, 2013, 31(2): 318-337.
[22] TURNBAUGH P J, LEY R E, MAHOWALD M A, et al. An obesity-associated gut microbiome with increased capacity for energy harvest[J]. Nature, 2006, 444(7 122): 1 027-1 031.
[23] 赵立平, 费娜. 肠道菌群与肥胖症的关系研究进展[J]. 微生物与感染, 2013, 8(2): 67-71.
[24] 崔燕丽, 徐晓芬, 吴正钧, 等. 乳酸菌胞外多糖对人类肠道菌群的影响 [J]. 中国微生态学杂志, 2016, 28(7): 851-856.
[25] ZHAO Li-ping, ZHANG Feng, DING Xiao-ying, et al. Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes[J]. Science, 2018, 359(6 380): 1 151-1 156.
[26] BAXTER N T, SCHMIDT A W, VENKATARAMAN A, et al. Dynamics of human gut microbiota and short-chain fatty acids in response to dietary interventions with three fermentable fibers[J]. mBio, 2019, 10(1): 1-13.
[27] BALLAL S A, GALLINI C A, SEGATA N, et al. Host and gut microbiota symbiotic factors: Lessons from inflammatory bowel disease and successful symbionts[J]. Cellular microbiology, 2011, 13(4): 508-517.
[28] PETNICKI-OCWIEJA T, HRNCIR T, LIU Y J, et al. Nod2 is required for the regulation of commensal microbiota in the intestine[J]. Proceedings of the National Academy of Sciences, 2009, 106(37): 15 813-15 818.
[29] 张圣方. 泰山蛹虫草多糖对免疫抑制小鼠肠道菌群和免疫调节功能的影响研究[D]. 泰安: 山东农业大学, 2015: 35-42.
[30] 王雪, 赵龙玉, 赵凤春. 应用Illumina高通量测序技术研究长根菇多糖对小鼠肠道菌群的影响[J]. 食品科学, 2015, 36(19): 222-226.
[31] KHAN I, HUANG Guo-xin, LI Xiao-ang, et al. Mushroom polysaccharides from Ganoderma lucidum and Poria cocos reveal prebiotic functions[J]. Journal of Functional Foods, 2018, 41: 191-201.
[32] ZHAO Rui-qiu, YANG Wen-jian, PEI Fei, et al. In vitro fermentation of six kinds of edible mushrooms and its effects on fecal microbiota composition[J]. LWT, 2018, 96: 627-635.
[33] XU Xiao-fei, YANG Ji-guo, NING Zheng-xiang, et al. Lentinula edodes-derived polysaccharide rejuvenates mice in terms of immune responses and gut microbiota [J]. Food Funct, 2015, 6(8): 2 653-2 663.
[34] XU S, DOU Y, YE B, et al. Ganoderma lucidum polysaccharides improve insulin sensitivity by regulating inflammatory cytokines and gut microbiota composition in mice[J]. Journal of Functional Foods, 2017, 38: 545-552.
[35] 徐晓飞. 香菇多糖L2的免疫调节机理研究[D]. 广州: 华南理工大学, 2014: 42-93.
[36] LUO Jian-ming, ZHANG Cheng, LIU Rong, et al. Ganoderma lucidum polysaccharide alleviating colorectal cancer by alteration of special gut bacteria and regulation of gene expression of colonic epithelial cells[J]. Journal of Functional Foods, 2018, 47: 127-135.
[37] LI Li-feng, LIU Hong-bing, ZHANG Quan-wei, et al. Comprehensive comparison of polysaccharides from Ganoderma lucidum and G. sinense: Chemical, antitumor, immunomodulating and gut-microbiota modulatory properties[J]. Sci Rep, 2018, 8(1): 1-12.
[38] CHEN Yu-qing, LIU Dan, WANG Ding-yi, et al. Hypoglycemic activity and gut microbiota regulation of a novel polysaccharide from Grifola frondosa in type 2 diabetic mice[J]. Food and Chemical Toxicology, 2019, 126: 295-302.
[39] LARSEN N, VOGENSEN F K, VAN D B F W J, et al. Gut microbiota in Human adults with type 2 diabetes differs from non-diabetic adults[J]. PLoS ONE, 2010, 5(2): e9085.
[40] SCHMIDT T S B, RAES J, BORK P. The human gut microbiome: From association to modulation[J]. Cell, 2018, 172(6): 1 198-1 215.