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Abstract

This article reviews the research progress of food polyphenols' intervention on type 2 diabetes and metabolic syndrome in recent years. And it expounds the possible mechanism of food polyphenols on hyperglycemia regulation. It is necessary to excavate more effective ingredient from food materials to provide more theoretical guidance for the development of hypoglycemic health food diabetics.

Publication Date

2-28-2019

First Page

202

Last Page

206

DOI

10.13652/j.issn.1003-5788.2019.02.038

References

[1] SINGH B, SINGH J P, KAUR A, et al. Phenolic composition and antioxidant potential of grain legume seeds: A review[J]. Food Research International, 2017, 101: 1-16.
[2] 张聪. 茶叶有效成分对糖尿病人健康管理的作用初论[J]. 福建茶叶, 2018, 40(10): 38.
[3] 钱荣立. 关于糖尿病的新诊断标准与分型[J]. 中国糖尿病杂志, 2000, 8(1): 5-6.
[4] KOPELMAN P G. Obesity as a medical problem[J]. Nature, 2000, 404(6 778): 635-643.
[5] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南: 2013年版[J]. 中国糖尿病杂志, 2014, 30(8): 893-942.
[6] YOONA K, JENNIFER K, PETER C. Polyphenols and Glycemic Control[J]. Nutrients, 2016, 8(1):17-44.
[7] ALBERTI K G M M, ECKEL R H, GRUNDY S M, et al. Harmonizing the metabolic syndrome[J]. Circulation, 2009, 120(16): 1 640-1 645.
[8] 丛维娜. 代谢综合征合并非酒精性脂肪肝炎小鼠模型的建立及银杏叶提取物治疗代谢综合征作用及其机制的探讨[D]. 北京: 中国协和医科大学, 2008: 47-73.
[9] 徐铭恩. 2型糖尿病/代谢综合症药物筛选及机制研究[D]. 杭州: 浙江大学, 2005: 15-20.
[10] 缪佳男. 安石榴苷对T2DM小鼠糖脂代谢及肝脏氧化应激的影响[D]. 北京: 北京中医药大学, 2018: 57-61.
[11] AMIOT M J, RIVA C, VINET A. Effects of dietary polyphenols on metabolic syndrome features in humans: a systematic review[J]. Obesity Reviews, 2016, 17(7): 573-586.
[12] VAN H M, GEURTS L, PLOVIER H, et al. Reduced obesity, diabetes and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier[J]. American Journal of Physiology Endocrinology & Metabolism, 2017, 314(4): 334-352.
[13] GUILFORD J M, PEZZUTO J M. Wine and health: a review[J]. American Journal of Enology & Viticulture, 2011, 62(4): 471-486.
[14] WU Chih-hsing, LU Feng-hwa, CHANG Chin-song, et al. Relationship among habitual tea consumption, percent body fat, and body fat distribution[J]. Obesity, 2012, 11(9): 1 088-1 095.
[15] GRASSI D, MULDER T P, DRAIJER R, et al. Black tea consumption dose-dependently improves flow-mediated dilation in healthy males[J]. Journal of Hypertension, 2009, 27(4): 774-781.
[16] RASOULI H, HOSSEINIGHAZVINI S M, ADIBI H, et al. Differential α-amylase/α-glucosidase inhibitory activities of plant-derived phenolic compounds: a virtual screening perspective for the treatment of obesity and diabetes[J]. Food & Function, 2017, 8(5): 1 942-1 954.
[17] CASTRO-ACOSTA M L, STONE S G, MOK J E, et al. Apple and blackcurrant polyphenol-rich drinks decrease postprandial glucose, insulin and incretin response to a high-carbohydrate meal in healthy men and women[J]. Journal of Nutritional Biochemistry, 2017(49): 53-62.
[18] 王振宇, 周丽萍, 刘瑜. 苹果多酚对小鼠脂肪代谢的影响[J]. 食品科学, 2010, 31(9): 288-291.
[19] CHANG Yun-ching, YANG Mon-yuan, CHEN Shu-chun, et al. Mulberry leaf polyphenol extract improves obesity by inducing adipocyte apoptosis and inhibiting preadipocyte differentiation and hepatic lipogenesis[J]. Journal of Functional Foods, 2016, 21: 249-262.
[20] COLLINS B, HOFFMAN J, MARTINEZ K, et al. A polyphenol-rich fraction obtained from table grapes decreases adiposity, insulin resistance, and markers of inflammation and impacts gut microbiota in high-fat fed mice[J]. The Journal of Nutritional Biochemistry, 2016, 31: 150-165.
[21] SCHINDLER C. The metabolic syndrome as an endocrine disease: is there an effective pharmacotherapeutic strategy optimally targeting the pathogenesis?[J]. Therapeutic Advances in Cardiovascular Disease, 2007, 1(1): 7-26.
[22] CUJIC N, SAVIKIN K, MILORADOVIC Z, et al. Characterization of dried chokeberry fruit extract and its chronic effects on blood pressure and oxidative stress in spontaneously hypertensive rats[J]. Journal of Functional Foods, 2018, 44: 330-339.
[23] IKARASHI N, TODA T, HATAKEYAMA Y, et al. Anti-hypertensive effects of acacia polyphenol in spontaneously hypertensive rats[J]. International Journal of Molecular Sciences, 2018, 19(3): 700-711.
[24] SUTHERLAND J P, MCKINLEY B, ECKEL R H. The metabolic syndrome and inflammation[J]. Metabolic Syndrome and Related Disorders, 2004, 2(2): 82-104.
[25] STULL A J, CASH K C, JOHNSON W D, et al. Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women[J]. Journal of Nutrition, 2010, 140(10): 1 764-1 768.
[26] LOCKYER S, ROWLAND I, SPENCER J P E, et al. Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial[J]. European Journal of Nutrition, 2017, 56(4): 1 421-1 432.
[27] CHUANG Chia-chi, MCINTOSH M K. Potential mechanisms by which polyphenol-rich grapes prevent obesity-mediated inflammation and metabolic diseases[J]. Annual Review of Nutrition, 2011, 31(1): 155-176.
[28] ROSILLO M , ALCARAZ M J, SNCHEZHIDALGO M, et al. Anti-inflammatory and joint protective effects of extra-virgin olive-oil polyphenol extract in experimental arthritis[J]. Journal of Nutritional Biochemistry, 2014, 25(12): 1 275-1 281.
[29] ROSILLO M , ALARCN-DE-LA-LASTRA C, CASTEJN M L, et al. Polyphenolic extract from extra virgin olive oil inhibits the inflammatory response in IL-1β-activated synovial fibroblasts[J]. British Journal of Nutrition, 2018, DOI: 10.1017/S0007114518002829.
[30] KAWAKAMI K, AKETA S, NAKANAMI M, et al. Major water-soluble polyphenols, proanthocyanidins, in leaves of persimmon (Diospyros kaki) and their α-amylase inhibitory activity[J]. Bioscience Biotechnology and Biochemistry, 2010, 74(7):1 380-1 385.
[31] ZHANG Yuan, LI Xing, WANG Zhe-zhi. Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents[J]. Food and Chemical Toxicology, 2010, 48(10): 2 656-2 662.
[32] 胡柏. 红米多酚降血糖作用的研究[D]. 无锡: 江南大学, 2015: 13-15.
[33] KIM Y, KEOGH J B, CLIFTON P M. Polyphenols and glycemic control[J]. Nutrients, 2016, 8(1): 17-43.
[34] 李兰. 绿茶提取物的降血糖研究[D]. 杭州: 浙江大学, 2014: 44-60.
[35] 李臻. 溪黄草多酚的提取、纯化、鉴定及生物活性研究[D]. 广州: 华南理工大学, 2013: 66-76.
[36] 扶雄, 张伟, 朱思明, 等. 香椿叶多酚的提取分离及其体外对糖尿病关键酶活性的抑制作用[J]. 现代食品科技, 2014, 30(7): 10-15.
[37] 仇菊, 朱宏, 卢林纲. 葡萄籽多酚对糖尿病大鼠的降血糖作用及其机制[J]. 食品科学, 2018, 39(1): 226-231.
[38] LI Rong, LIANG Tao, XU Liang-yuan, et al. Protective effect of cinnamon polyphenols against STZ-diabetic mice fed; high-sugar, high-fat diet and its underlying mechanism[J]. Food & Chemical Toxicology, 2013, 51(1): 419-425.
[39] 刘海珍, 宋桂花. 葡多酚与糖尿病氧化应激[C]// 全国中西医结合营养学术会议论文. 青岛: 中国中西医结合学会, 2014: 242-243.
[40] BANIHANI S, SWEDAN S, ALGURAAN Z. Pomegra-nate and type 2 diabetes[J]. Nutrition Research, 2013, 33(5): 341-348.
[41] 肖更生, 万利秀, 徐玉娟, 等. 柑橘皮黄酮降血糖作用的研究[J]. 现代食品科技, 2013, 29(4): 698-701.
[42] POLCE S A, BURKE C, FRANA L M, et al. Ellagic acid alleviates hepatic oxidative stress and insulin resistance in diabetic female rats[J]. Nutrients, 2018, 10(5): 531-545.
[43] 王艳. 几种膳食多酚抑制STZ诱导大鼠糖尿病形成分子机制[D]. 长沙: 湖南农业大学, 2012: 49-67.
[44] TSAI H Y, WU L Y, HWANG L S. Effect of a proanthocyanidin-rich extract from longan flower on markers of metabolic syndrome in fructose-fed rats[J]. Journal of Agricultural and Food Chemistry, 2008, 56(22): 11 018-11 024.
[45] 王峰, 李新明, 李群, 等. 苹果多酚及其活性单体对糖尿病小鼠肾中与糖代谢相关基因表达的影响[J]. 中国医药指南, 2018, 16(17): 1-2.
[46] 耿艳艳, 王岳飞. 茶多酚防治糖尿病作用及其机理的研究进展[J]. 茶叶, 2007, 33(1): 7-10.
[47] 邹宇晓, 廖森泰, 刘军, 等. 桑椹降血糖保健食品开发展现状与趋势[C]// 全国蚕桑资源多元化利用学术研讨会. 湖州: 中国蚕学会, 2014: 128-129.
[48] 郭颖, 辛念, 戴荣继. 天然黄酮类化合物治疗2型糖尿病的机制研究进展[J]. 天然产物研究与开发, 2017, 29(10): 1 805-1 811.
[49] CARDONA F, ANDRS-LACUEVA C, TULIPANI S, et al. Benefits of polyphenols on gut microbiota and implications in human health[J]. Journal of Nutritional Biochemistry, 2013, 24(8): 1 415-1 422.
[50] ANH F F, DESJARDINS Y, PILON G, et al. Polyphenols and type 2 diabetes: A prospective review[J]. Pharmanutri-tion, 2013, 1(4): 105-114.

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