Preparation of water-soluble resveratrol/HP-β-CD microcapsule by spray drying method

Authors

TANG Hongwei, College of Material Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China
KUANG Chuntao, College of Material Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China
XIANG Shu, College of Material Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China
LI Xiangzhou, College of Material Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China
YANG Ting, College of Material Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China
YI Xiangguang, College of Material Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China

Abstract

Hydroxypropyl-β-cyclodextrin (HP-β-CD) was used to improve water solubility of Res. The preparation conditions of Res/HP-β-CD microcapsule by spray drying method were optimized, and Res/HP-β-CD microcapsule was confirmed by UV, IR and SEM. The results showed that optimum preparation conditions of Res/HP-β-CD microcapsule were mass ratio of Res to HP-β-CD for 1∶5, stirring at 30 ℃, feed flow rate for 2.1 mL/min and inlet-air temperature for 140 ℃. The rate of drug-loading and the solubility of Res were 15.18% and 12.75 g/L, respectively, under the optimum conditions. UV, IR and SEM tests of Res/HP-β-CD microcapsule demonstrated that the aqueous solubility of Res increased due to the microcapsule formation between Res and HP-β-CD by hydrogen bond and hydrophobic forces, and the decrease of particle size.

Publication Date

4-28-2019

First Page

192

Last Page

196

DOI

10.13652/j.issn.1003-5788.2019.04.035

Recommended Citation

Hongwei, TANG; Chuntao, KUANG; Shu, XIANG; Xiangzhou, LI; Ting, YANG; and Xiangguang, YI (2019) "Preparation of water-soluble resveratrol/HP-β-CD microcapsule by spray drying method," Food and Machinery: Vol. 35: Iss. 4, Article 35.
DOI: 10.13652/j.issn.1003-5788.2019.04.035
Available at: https://www.ifoodmm.cn/journal/vol35/iss4/35

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