Subchronic toxicity of Cerasus lannesiana albo-roseain in rats

Authors

ZHANG Cheng-xiang, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166 , China ；Safety Assessment and Research Center for Drug, Pesticide and Veterinary Drug of Jiangsu Province,Nanjing, Jiangsu 211166 , China
LI Shi-fen, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166 , China ；Safety Assessment and Research Center for Drug, Pesticide and Veterinary Drug of Jiangsu Province,Nanjing, Jiangsu 211166 , China
WANG Yu-bang, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166 , China ；Safety Assessment and Research Center for Drug, Pesticide and Veterinary Drug of Jiangsu Province,Nanjing, Jiangsu 211166 , China
ZHANG Lu-lu, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166 , China ；Safety Assessment and Research Center for Drug, Pesticide and Veterinary Drug of Jiangsu Province,Nanjing, Jiangsu 211166 , China
YAN Ting, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166 , China ；Safety Assessment and Research Center for Drug, Pesticide and Veterinary Drug of Jiangsu Province,Nanjing, Jiangsu 211166 , China
ZHU Xue-feng, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166 , China ；Safety Assessment and Research Center for Drug, Pesticide and Veterinary Drug of Jiangsu Province,Nanjing, Jiangsu 211166 , China

Abstract

A total of 100 SD rats, half male and half female, were randomly divided into untreated control group (C1 group), treated control group (C2 group), low dose group (Ⅰgroup), middle dose group (Ⅱ group), and high dose group (Ⅲ group). The rats were fed continuously for 13 weeks, and the body weight, food intake, blood routine indexes, blood biochemical indexes, urine routine indexes, main organ weights and pathological histological examination of the organs were observed. Results: There was no significant difference between the observation groups (P＞0.05). The pathological changes related to Cerasus lannesiana Albo-rosea were not found in the pathological examination of the main organs. No harmful effects were observed and it was found safe when SD rats were fed with Cerasus lannes-iana Albo-rosea of human recommended doses for 160 times.

Publication Date

2-28-2020

First Page

56

Last Page

61,164

DOI

10.13652/j.issn.1003-5788.2020.02.010

Recommended Citation

Cheng-xiang, ZHANG; Shi-fen, LI; Yu-bang, WANG; Lu-lu, ZHANG; Ting, YAN; and Xue-feng, ZHU (2020) "Subchronic toxicity of Cerasus lannesiana albo-roseain in rats," Food and Machinery: Vol. 36: Iss. 2, Article 10.
DOI: 10.13652/j.issn.1003-5788.2020.02.010
Available at: https://www.ifoodmm.cn/journal/vol36/iss2/10

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