Abstract
To study the effect of short-term intake of high edible oil on the viscera coefficient and gastrointestinal motility in mice and providing the basis for rational dietary oil, 10 SPF KM mice were randomly divided into the control group and the edible oil group. The mice in the edible oil group were given edible oil twice a day, 0.3 mL each time, according to 20 mL/(kg·d) and mace in the control group were given equal amounts of distilled water for 13 days. The viscera coefficient and gastrointestinal motility of mice were compared. It was found that the dietary amount of edible oil group decreased and the amount of drinking water increased. Compared with the control group, edible oil reduced the coefficients of liver, spleen and thymus in mice, but the difference was not statistically significant (P＞0.05). In terms of gastrointestinal motility, edible oil could increase the small intestine propulsion rate of mice and slow down the gastric emptying rate of mice, with no statistically significant difference compared with the control group (P＞0.05). The content of serum D-xylose in the control group was higher than that in the edible oil group, but the difference was still not statistically significant (P＞0.05). The study indicated that short-term high intake of edible oil had little effect on viscera coefficient and gastrointestinal motility in mice.
Publication Date
2-18-2023
First Page
41
Last Page
44
DOI
10.13652/j.issn.1003-5788.2020.08.007
Recommended Citation
Tao, ZHENG and Yun-shan, HE
(2023)
"Effect of short-term intake of high edible oil on viscera coefficient and gastrointestinal motility in mice,"
Food and Machinery: Vol. 36:
Iss.
8, Article 7.
DOI: 10.13652/j.issn.1003-5788.2020.08.007
Available at:
https://www.ifoodmm.cn/journal/vol36/iss8/7
References
[1] 刘娅薇,惠华英,谭周进.食用油对身体健康的影响及与肠道菌群的关系[J].世界华人消化杂志,2019,27(9):583-588.
[2] 朱航榉,王锋,杨贤,等.不同油脂对小鼠肠道菌群的影响[J].环境与职业医学,2017,34(11):995-998.
[3] 黄海滨.平衡油脂对小鼠脂代谢的影响及其机理研究[D].长沙:湖南农业大学,2015:1-4.
[4] 孙建新,安娟,连军.影响实验动物脏器重量及脏器系数因素分析[J].实验动物科学,2009,26(1):49-51.
[5] 李韵峰,马俊峰.影响实验动物脏器重量及脏器系数因素分析[J].畜牧业环境,2020,26(10):39.
[6] 李习雄.焦槟榔消食导滞作用机制的实验研究[D].成都:成都中医药大学,2016:11-12.
[7] 梁生林,许日祥,吴金金,等.厚朴皮、叶、花水提物对小鼠胃肠动力作用的比较研究[J].井冈山大学学报(自然科学版),2016,37(3):76-79.
[8] 陈奇.中药药理研究方法学[M].北京:人民卫生出版社,2006:437-438.
[9] 崔小兵,孙学,文红梅,等.不同加工方式的中药白术对脾虚大鼠唾液淀粉酶活性和尿中D-木糖排泄率的影响[J].中国中药杂志,2016,41(14):2 576-2 580.
[10] 郝菲菲,刘婉青,聂克.连翘对小鼠胃肠动力影响的实验研究[J].山东中医药大学学报,2018,42(4):351-353,376.
[11] 曾禹.中国城乡居民实际油脂摄入量(猪油、葵花籽油及其复合油)对肥胖和血糖稳态的影响研究[D].长沙:湖南农业大学,2018:1-2.
[12] 中国营养学会.中国居民膳食指南:2016[M].北京:人民卫生出版社,2016:3.
[13] 姜洪林,翟兴会,金刚.小儿健身消食颗粒对脾虚证动物模型的影响[J].长春中医学院学报,2001,17(3):46.
[14] 古兰·托合提木拉提,叶尔努尔·吐苏甫汗,马玉兰,等.高脂肪饮食暴露对雌性大鼠子代糖脂代谢和卵巢功能的影响[J].中国医师杂志,2019,21(9):1 308-1 311.
[15] 黄子逸,陈铎,叶心语,等.不同加热时间的食用油对雄性小鼠血脂与微量元素的影响[J].环境与职业医学,2018,35(5):418-422.
[16] 杨晓燕,何云山,谭周进,等.不同剂量植物油对小鼠肠道微生物、酶活性及血常规的影响[J/OL].食品与发酵工业.[2020-06-30].https://doi.org/10.13995/j.cnki.11-1802/ts.023375.
[17] 田徐露,蓝程,岑运光,等.积雪草总苷对老年消化不良模型大鼠胃肠动力及肠神经系统的保护作用量效关系及机制研究[J].中国药房,2020,31(12):1 429-1 435.
[18] 张明,吴晶,彭真,等.荷泽颗粒对脾虚大鼠血清胃泌素、D-木糖浓度、磷酸肌酸激酶的影响[J].中国中医急症,2020,29(2):267-269,277.
[19] 何云山,惠华英,喻嵘,等.芦笋对高脂饮食小鼠脏器指数及血生化的影响[J].中国微生态学杂志,2018,30(11):1 261-1 265.
[20] 高青松.不同类型脂肪酸对SD大鼠血清脂肪酸及胰岛素抵抗的影响[D].北京:中国人民解放军军事医学科学院,2010:2-4.
[21] 高珊,童英,阎向东,等.常用食用油对大鼠脏器、生化指标及脂质过氧化的影响[J].毒理学杂志,2006,20(4):251-253.
[22] DUBNOV G,BERRY E M.Polyunsaturated fatty acids,insulin resistance,and atherosclerosis:Is inflammation the connecting link[J].Metab Syndr Relat Disord,2004,2(2):124-128.
[23] KEROS S,MCBAIN C J.Arachidonic acid inhibits transient potassium currents and broadens action potentials during electrographic seizures in hippocampal pyramidal and inhibitory interneurons[J].J Neurosci,1997,17(10):3 476-3 487.
[24] 崔艺峰.不饱和脂肪酸在牵张增强豚鼠胃窦平滑肌细胞毒蕈碱电流中的作用[D].延吉:延边大学,2003:1-4.
[25] 刘娅薇,惠华英,谭周进.脑肠轴传输中的胃肠肽类激素[J].世界华人消化杂志,2019,27(16):1 007-1 012.
[26] DESBONNET L,GARRETT L,CLARKE G,et al.Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression[J].Neuroscience,2010,170(4):1 179-1 188.