Abstract
Different types of in vitro digestion conditions and digestion parts were categorized summarized in this review, and different types of in vitro simulated digestion tests were analyzed. The application of in vitro simulated digestion in different nutrients was also reviewed.
Publication Date
3-28-2021
First Page
201
Last Page
206
DOI
10.13652/j.issn.1003-5788.2021.03.036
Recommended Citation
Nuo, LI; Dong-jie, ZHANG; Gui-fang, ZHANG; and Bao-xin, LU
(2021)
"Advances in the study of in vitro simulated digestion,"
Food and Machinery: Vol. 37:
Iss.
3, Article 36.
DOI: 10.13652/j.issn.1003-5788.2021.03.036
Available at:
https://www.ifoodmm.cn/journal/vol37/iss3/36
References
[1] 陈责, 贾慧. 体外消化模型的研究进展[J]. 农产品加工, 2017(9): 61-64, 68.
[2] 李占明, 俞玥, 梁奕, 等. 体外模拟消化过程中果胶对竹叶黄酮生物可及性的影响[J]. 食品科学, 2020, 41(11): 43-49.
[3] KONG F, SINGH R P. A human gastric simulator (HGS) to study food digestion in human stomach[J]. Journal of Food Science, 2010, 75(9): E627-E635.
[4] LAIRD B D, TR V D W, CORRIVEAU M C, et al. Gastrointestinal microbes increase arsenic bioaccessibility of ingested mine tailings using the simulator of the human intestinal microbial ecosystem[J]. Environmental Science & Technology, 2007, 41(15): 5 542-5 547.
[5] FERIAGERVASIO D, TOTTEY W, GACI N, et al. Three-stage continuous culture system with a self-generated anaerobia to study the regionalized metabolism of the human gut microbiota[J]. Journal of Microbiological Methods, 2014, 96(1): 111-118.
[6] ASTWOOD J D, LEACH J N, FUCHS R L. Stability of food allergens to digestion in vitro[J]. Nature Biotechnol, 1996, 14: 1 269-1 273.
[7] BUBLIN M, RADAUER C, KNULST A, et al. Effects of gastrointestinal digestion and heating on the allergenicity of the kiwiallergens Act d1, actinidin, and Act d2, a thaumatin-like protein[J]. Molecular Nutrition and Food Research, 2008, 52: 1 130-1 139.
[8] 刘光明, 钟永嘉, 曹敏杰, 等. 鲤鱼过敏原的体外模拟消化[J]. 集美大学学报(自然科学版), 2010(4): 267-271.
[9] MINEKUS M, ALMINGER M, ALVITO P, et al. A standardised static in vitro digestion method suitable for food: An international consensus[J]. Food & Function, 2014, 5(6): 1 113-1 124.
[10] 古成. 魔芋甘露聚糖稳定姜黄素纳米乳状液及其缓释消化研究[D]. 哈尔滨: 哈尔滨工业大学, 2019: 43-62.
[11] 游义娇, 佟平, 袁娟丽, 等. 食物蛋白质体外消化模型研究进展[J]. 食品工业科技, 2017, 38(6): 381-385.
[12] VARDAKOU M, MERCURI A, BARKER S A, et al. Achieving antral grinding forces in biorelevant in vitro models: Comparing the USP dissolution apparatus II and the dynamic gastric model with human in vivo data[J]. AAPS Pharm Sci Tech, 2011, 12(2): 620-626.
[13] 许芳溢, 李五霞, 吕曼曼, 等. 苦荞芽粉馒头体外消化后抗氧化能力研究[J]. 中国粮油学报, 2014, 29(12): 16-22.
[14] 熊文, 吴婷, 曹伟伟, 等. 体外消化对藜蒿叶多酚含量及抗氧化活性的影响[J]. 现代食品科技, 2020, 36(1): 78-83, 287.
[15] 闵芳芳, 聂少平, 万宇俊, 等. 青钱柳多糖在体外消化模型中的消化与吸收[J]. 食品科学, 2013, 34(21): 24-29.
[16] BLANQUET S, EVELIJIN Z, BEYSSAC E, et al. A dynamic artificial gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions[J]. Pharmaceutical Research, 2004, 21(4): 585-591.
[17] 陆俊, 敦惠瑜, 向孝哲, 等. 体外模拟胃、肠消化对6种黑色食品抗氧化成分及其活性的影响[J]. 食品科学, 2018, 39(5): 47-56.
[18] 靳志强, 陈艳彬, 王玺. 湿热处理和发酵对小米营养素生物可给性及淀粉消化性的影响[J]. 中国食品学报, 2019, 19(12): 177-186.
[19] 贾雨朦. 骏枣—树莓—滁菊复配粉吸湿性调控与消化前后抗氧化及生物活性研究[D]. 沈阳: 沈阳农业大学, 2019: 36-37.
[20] 徐洪宇, 蒯宜蕴, 詹壮壮, 等. 果皮中酚类物质含量、抗氧化活性及在体外消化过程中成分的变化[J]. 食品科学, 2019, 40(15): 23-30.
[21] 徐箐, 柳嘉, 林静, 等. 低GI淀粉原料的筛选及理化特性和体外消化特性的研究[J]. 食品研究与开发, 2020, 41(20): 8-14.
[22] 柳芳伟, 张珊珊, 陈苏明, 等. 三种富含多糖面包的体外消化酵解特性[J/OL]. 食品科学. (2020-03-23) [2020-11-11]. http://kns.cnki.net/kcms/detail/11.2206.TS.20200320.2320.044.html.
[23] 黄强, 王婵, 罗发兴, 等. 玉米淀粉的热力学性质与消化性[J]. 华南理工大学学报(自然科学版), 2011, 39(9): 7-11.
[24] 张天财. 鲜核桃保鲜及核桃种皮中多酚化合物的测定、纯化及功能研究[D]. 云南: 昆明理工大学, 2014: 4-6.
[25] 倪香艳, 钟葵, 佟立涛, 等. 糙米体外消化过程中酚类物质含量及抗氧化活性[J]. 食品科学, 2018, 39(16): 105-111.
[26] MAIARA J S, GENI R S, GLRIA M G, et al. Regular and decaffeinated espresso coffee capsules: Unravelling the bioaccessibility of phenolic compounds and their antioxidant properties in milk model system upon in vitro digestion[J]. LWT, 2021, 135: 110255.
[27] MA Yi-long, GAO Jie, WEI Zhao-jun, et al. Effect of in vitro digestion on phenolics and antioxidant activity of red and yellow colored pea hulls[J]. Food Chemistry, 2021, 337: 127606.
[28] LIU Xiao-juan, ZHANG Ruo-jie, MCCLEMENTS D J, et al. Nanoemulsion-based delivery systems for nutraceuticals: Influence of long-chain triglyceride (LCT) type on in vitro digestion and astaxanthin bioaccessibility[J]. Food Biophysics, 2018, 13(4): 412-421.
[29] GARRETT D A, FAILLA M L, SARAMA R J. Development of an in vitro digestion method to assess carotenoid bioavailability from meals[J]. Journal of Agricultural and Food Chemistry, 1999, 47(10): 4 301-4 309.
[30] 雷菲, 高彦祥, 侯占群. 体外消化过程中影响类胡萝卜素生物利用率的因素[J]. 食品科学, 2012, 33(21): 368-373.
[31] 杜佳, 余诚玮, 陈莉, 等. 体外消化和贮藏条件对粗壮脉纹孢菌孢子中类胡萝卜素稳定性的影响[J]. 食品科学, 2018, 39(17): 86-91.
[32] PEREZ-VICENTE A, GIL-IZQUIERDO A, GARCIAA-VIGUERA C. In vitro gastrointestinal digestion study of pomegranate juice phenolic compounds, anthocyanins, and vitamin C[J]. Agriculture and Food Chemistry, 2002, 50(8): 2 308-2 312.
[33] 张艳芳, 董平, 梁兴国. 食物成分消化模型的研究进展[J]. 食品工业技, 2013, 34(18): 356-361.
[34] ABDEL-AAL E S M. Effects of baking on protein digestibility of organic spelt products determined by two in vitro digestion methods[J]. LWT-Food Science and Technology, 2008, 41(7): 1 282-1 288.
[35] WANG Xian-sheng, TANG Chuan-he, YANG Xiao-quan, et al. Characterization, amino acid composition and in vitro digestibility of hemp (Cannabis sativa L.) proteins[J]. Food Chemistry, 2007, 107(1): 11-18.
[36] 甄红敏, 栾广忠, 胡新中, 等. 灭酶方法对燕麦淀粉和蛋白质体外消化特性的影响[J]. 麦类作物学报, 2011, 31(3): 475-479.
[37] GONZLEZ-MONTOYA M, HERNNDEZ-LEDESMA B, SILVN J M, et al. Peptides derived from in vitro gastrointestinal digestion of germinated soybean proteins inhibit human colon cancer cells proliferation and inflammation[J]. Food Chemistry, 2018, 242: 75-82.
[38] 岳颖, 严斌, 刘丽娅, 等. 小麦蛋白水解物对肠道上皮细胞抵御氧化应激损伤的作用[J]. 中国食品学报, 2020, 20(10): 68-75.
[39] 环境保护部. 污染场地风险评估技术导则: HJ 25.3—2014[S]. 北京: 中国标准出版社, 2014: 1-53.
[40] 唐翔宇, 朱永官, 陈世宝. In Vitro 法评估铅污染土壤对人体的生物有效性[J]. 环境化学, 2003, 22(5): 503-506.
[41] 李华, 李海龙, 朱宇恩, 等. 基于人体可给性的重金属污染场地健康风险评价[J]. 地球环境学报, 2015, 6(1): 60-66.
[42] CASTEEL S W, WEIS C P, HENNINGSEN G M, et al. Estimation of relative bioavailability of lead in soil and soil-like materials using young swine[J]. Environmental Health Perspectives, 2006, 114(8): 1 162-1 171.
[43] 张东平, 余应新, 张帆, 等. 环境污染物对人体生物有效性测定的胃肠模拟研究现状[J]. 科学通报, 2008(21): 2 537-2 545.
[44] RUBY M V, DAVIS A, SCHOOF R, et al. Estimation of lead and arsenic bioavailability using a physiologically based extraction test[J]. Environmental Science & Technology, 1996, 30(2): 422-430.
[45] APPLETON J D, CAVE M R, WRAGG J. Modelling lead bioaccessibility in urban topsoils based on data from Glasgow, London, Northampton and Swansea, UK[J]. Environmental Pollution, 2012, 171(4): 265-272.
[46] ROBIN R R, NICHOLAS T B, STAN W C, et al. An in vitro gastrointestinal method to estimate bioavailable arsenic in contaminated soils and solid media[J]. Environmental Science & Technology, 1999, 33(4): 642-649.
[47] WRAGG J, CAVE M, TAYLOR H, et al. Inter-laboratory trial of a unified bioaccessibility testing procedure[R]. [S.l.]: NERC, 2009.
[48] 陈廷廷, 侯艳伟, 蔡超, 等. 应用四种体外消化方法比较研究场地土壤中重金属的生物可给性及其人体健康风险[J]. 环境化学, 2018, 37(11): 2 342-2 350.
[49] 吴小飞. 基于体外提取方法对土壤重金属生物可给性的研究与评价[D]. 扬州: 扬州大学, 2015: 4-38.
[50] KIOMARS Sharafi, RAMIN Nabizadeh Nodehi, AMIR Hossein Mahvi, et al. Bioaccessibility analysis of toxic metals in consumed rice through an in vitro human digestion model-Comparison of calculated human health risk from raw, cooked and digested rice[J]. Food Chemistry, 2019, 299: 125126.
[51] 吕倩, 李欣, 吴跃, 等. 大米主食制品中污染物镉的体外消化释放研究[J]. 中国粮油学报, 2017, 32(11): 1-7.