Research progress on the determination of free-base nicotine in tobacco and tobacco products

Authors

ZHANG Hao, China National Tobacco Quality Supervision and Test Centre, Key Laboratory of Tobacco Biological Effects, Zhengzhou, Henan 450001 , China
HAN Shu-lei, China National Tobacco Quality Supervision and Test Centre, Key Laboratory of Tobacco Biological Effects, Zhengzhou, Henan 450001 , China
CHEN Huan, China National Tobacco Quality Supervision and Test Centre, Key Laboratory of Tobacco Biological Effects, Zhengzhou, Henan 450001 , China
HOU Hong-wei, China National Tobacco Quality Supervision and Test Centre, Key Laboratory of Tobacco Biological Effects, Zhengzhou, Henan 450001 , China
HU Qing-yuan, China National Tobacco Quality Supervision and Test Centre, Key Laboratory of Tobacco Biological Effects, Zhengzhou, Henan 450001 , China

Abstract

The research progress on determination of free-base nicotine in tobacco and tobacco products in the past 30 years was reviewed and discussed, including solvent extraction method, headspace solid-phase microextraction method,1H NMR, Henderson-Hasselbalch method and spectroscopy method, etc. Advantages and limitations of each method were summarized and discussed and the development in this field was prospected.

Publication Date

7-20-2022

First Page

234

Last Page

240

DOI

10.13652/j.spjx.1003.5788.2022.90025

Recommended Citation

Hao, ZHANG; Shu-lei, HAN; Huan, CHEN; Hong-wei, HOU; and Qing-yuan, HU (2022) "Research progress on the determination of free-base nicotine in tobacco and tobacco products," Food and Machinery: Vol. 38: Iss. 4, Article 38.
DOI: 10.13652/j.spjx.1003.5788.2022.90025
Available at: https://www.ifoodmm.cn/journal/vol38/iss4/38

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