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Abstract

The main functional components and biological activities of Grifola frondosa were reviewed, and the existing problems and future research directions were also discussed.

Publication Date

10-16-2022

First Page

234

Last Page

240

DOI

10.13652/j.spjx.1003.5788.2022.90086

References

[1] CHEN X,JI H,XU X,et al.Optimization of polysaccharide extraction process from Grifola frondosa and its antioxidant and anti-tumor research[J].Journal of Food Measurement and Characterization,2019,13:144-153.
[2] COHEN N,COHEN J,ASATIANI M D,et al.Chemical composition and nutritional and medicinal value of fruit bodies and submerged cultured mycelia of culinary-medicinal higher basidiomycetes mushrooms[J].International Journal of Medicinal Mushrooms,2014,16:273-291.
[3] 于荣利,张桂玲,秦旭升.灰树花研究进展[J].上海农业学报,2005,21(3):101-105.YU R L,ZHANG G L,QIN X S.Advances in study on Grifola frondosa[J].Acta Agriculturae Shanghai,2005,21(3):101-105.
[4] 马青,陈石良.灰树花保健饮料加工工艺的研究[J].食品与机械,2003(3):22-23.MA Q,CHEN S L.Technology study of healthy drink of Grifola frondosa[J].Food & Machinery,2003(3):22-23.
[5] 方东路,马晓惠,赵明文,等.添加灰树花粉面团的酶法改性及面条品质评价[J].食品科学,2021,42(10):23-31.FANG D L,MA X H,ZHAO M W,et al.Enzymatic modifification of dough added with Grifola frondosaflour and quality evaluation of noodles made from it[J].Food Science,2021,42(10):23-31.
[6] 张冰茹,邬雨季,刘维明,等.灰树花多糖的制备及药理活性的研究进展[J].食药用菌,2019,27(2):99-105.ZHANG B R,WU Y J,LIU W M,et al.Research progress on preparation and pharmacological activities of polysaccharide from Grifola frondosa[J].Edible and Medicinal Mushrooms,2019,27(2):99-105.
[7] MENG M,CHENG D,HAN L,et al.Isolation,purification,structural analysis and immunostimulatory activity of water-soluble polysaccharides from Grifola frondosa fruiting body[J].Carbohydrate Polymers,2017,157:1 134-1 143.
[8] WANG Y,SHEN X,LIAO W,et al.A heteropolysaccharide,L-fuco-D-manno-1,6-α-D-galactan extracted from Grifola frondosa and antiangiogenic activity of its sulfated derivative[J].Carbohydrate Polymers,2014,101:631-641.
[9] ZHANG Y,CHEN Z,HUANG Z,et al.A comparative study on the structures of Grifola frondosa polysaccharides obtained by different decolourization methods and their in vitro antioxidant activities[J].Food & Function,2019,10:6 720-6 731.
[10] LI Q,ZHANG F,CHEN G,et al.Purification,characterization and immunomodulatory activity of a novel polysaccharide from Grifola frondosa[J].International Journal of Biological Macromolecules,2018,111:1 293-1 303.
[11] ZHAO C,GAO L,WANG C,et al.Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71[J].Carbohydrate Polymers,2016,144:382-389.
[12] CHEN Y,LIU Y,SARKER M M R,et al.Structural characterization and antidiabetic potential of a novel heteropolysaccharide from Grifola frondosa via IRS1/PI3K-JNK signaling pathways[J].Carbohydrate Polymers,2018,198:452-461.
[13] SU C,LU M,LU T,et al.A(1→6)-branched(1→4)-β-D-glucan from Grifola frondosa inhibits lipopolysaccharide-induced cytokine production in RAW264.7 macrophages by binding to TLR2 rather than Dectin-1 or CR3 receptors[J].Journal of Natural Products,2020,83:231-242.
[14] CHEN Y,LIU D,WANG D,et al.Hypoglycemic activity and gut microbiota regulation of a novel polysaccharide from Grifola frondosa in type 2 diabetic mice[J].Food and Chemical Toxicology,2019,126:295-302.
[15] LIU C,JI H,WU P,et al.The preparation of a cold-water soluble polysaccharide from Grifola frondosa and its inhibitory effects on MKN-45 cells[J].Glycoconjugate Journal,2020,37:413-422.
[16] NANBA H,HISHIDA I,KURODA H.Antitumor activity exhibited by orally administered extract from fruit body of Grifola frondosa(maitake)[J].Chemical & Pharmaceutical Bulletin,1988,36(5):1 819-1 827.
[17] KUBO K,AOKI H,NANBA H.Anti-diabetic activity present in the fruit body of Grifola frondosa(Maitake)[J].Biol Pharm Bull,1994,17(8):1 106-1 110.
[18] MA X,LI C,QI W,et al.Protective effect of extracellular polysaccharides from Grifola frondosa mycelium on CCl4-injured liver in vitro[J].Bioactive Carbohydrates and Dietary Fibre,2015,6(1):7-14.
[19] NANBA H,HAMAGUCHI A,KURODA H.The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa(Maitake)[J].Chem Pharm Bull,1987,35(3):1 162-1 168.
[20] XU H,LIU J,SHEN Z,et al.Analysis of chemical composition,structure of Grifola frondosa polysaccharides and its effect on skin TNF-α levels,lgG content,T lymphocytes rate and caspase-3 mRNA[J].Carbohydrate Polymers,2010,82(3):687-691.
[21] ISHIZUKA T,YAOITA Y,KIKUCHI M.Sterol constituents from the fruit bodies of Grifola frondosa(FR.)S.F.GRAY.[J].Cheminform,2010,29(18):1 756-1 760.
[22] ZHANG Y J,MILLS G L.Cyclooxygenase inhibitory and antioxidant compounds from the mycelia of the edible mushroom Grifola frondosa[J].Journal of Agricultural and Food Chemistry,2002,20(26):7 581-7 585.
[23] 庞菲.灰树花化学成分及抗肿瘤细胞增殖作用研究[D].上海:华东师范大学,2010:12-39.PANG F.Chemical constituents and antiproliferative of Grifola frondosa on cancer cell line[D].Shanghai:East China Normal University,2010:12-39.
[24] CHEN S D,YONG T Q,XIAO C,et al.Pyrrole alkaloids and ergosterols from Grifola frondosa exert anti-α-glucosidase and anti-proliferative activities[J].Journal of Functional Foods,2018,43:196-205.
[25] 陈向东,刘晓雯,吴梧桐.灰树花多酚的提取和活性研究[J].食品与生物技术学报,2005,24(4):26-30.CHEN X D,LIU X W,WU W T.Extraction and activities of polyphenol from Grifola frondosa mycelium[J].Journal of Food and Biotechnology,2005,24(4):26-30.
[26] 柴丽.灰树花多酚与多糖的分离提取及活性研究[D].大连:大连工业大学,2012:32-37.CHAI L.Studies on the extraction of polyphenols and polysacchaides from Grifola frondosa and their activies[D].Dalian:Dalian Polytechnic University,2012:32-37.
[27] 吕旭聪,贾瑞博,李燕,等.灰树花抗氧化活性多酚的提取纯化及其鉴定[J].中国酿造,2016,35(3):74-79.LU X C,JIA R B,LI Y,et al.Purification and identification of polyphenols with antioxidant activity from Grifola frondosa[J].China Brewing,2016,35(3):74-79.
[28] 李燕.灰树花活性组分改善脂质代谢紊乱作用研究[D].福州:福建农林大学,2017:25-34.LI Y.The study on effect of active components from Grifola frondosa on lipid metabolic disorder[D].Fuzhou:Fujian Agriculture and Forestry University,2017:25-34.
[29] 李炜男.罗非鱼皮抗冻肽制备及其对鼠李糖乳杆菌ATCC7469抗冻保护机理研究[D].舟山:浙江海洋大学,2021:54.LI W N.Preparation of antifreeze peptide from tilapia skin and its antifreeze protection mechanism on Lactobacillus rhamnosus ATCC7469[D].Zhoushan:Zhejiang Ocean University,2021:54.
[30] 方磊,王雨辰,张海欣.南极磷虾肽的脱氟工艺和体外抗氧化作用[J].食品工业,2020,41(11):119-123.FANG L,WANG Y C,ZHANG H X.Defluorination of antarctic krill peptide and antioxidant effect in vitro[J].Food Industry,2020,41(11):119-123.
[31] 朱玲.酶解豌豆肽的制备及其ACE抑制活性研究[D].郑州:河南工业大学,2014:48.ZHU L.Study on the preparation and ACE inhibitory activity of pea peptides[D].Zhengzhou:Henan University of Technology,2014:48.
[32] 许锐.灰树花鲜味肽的制备及关键滋味物质研究[D].上海:上海应用技术大学,2020:33-44.XU R.Study on the preparation of umami peptides and key taste-active compounds from Grifola frondosa mushroom[D].Shanghai:Shanghai University of Applied Technology,2020:33-44.
[33] 陈贵堂,周琼飞,朱艳丽,等.采用美拉德反应提高灰树花多肽的抗氧化活性[J].食品科学,2013,34(14):26-29.CHEN G T,ZHOU Q F,ZHU Y L,et al.Improving of the antioxidant activity of Grifola frondosa peptides by maillard reaction[J].Food Science,2013,34(14):26-29.
[34] 马迪,冯娜,韩伟.灰树花子实体的化学成分研究[J].食用菌学报,2015,22(3):80-84.MA D,FENG N,HAN X.Chemical components of Grifola frondosa fruiting bodies[J].Acta Edulis Fungi,2015,22(3):80-84.
[35] LIN H,ChUENG S W,NESIN M,et al.Enhancement of umbilical cord blood cell hematopoiesis by maitake beta-glucan is mediated by granulocyte colony-stimulating factor production[J].Clinical and Vaccine Immunology,2007,14(1):21-27.
[36] WANG Y,SHEN X,LIAO W,et al.A heteropolysaccharide,l-fuco-d-manno-1,6-α-d-galactan extracted from Grifola frondosa and antiangiogenic activity of its sulfated derivative[J].Carbohydrate Polymers,2014,101:631-641.
[37] ROLDAN-DEAMICIS A,ALONSO E,BRIE B,et al.Maitake Pro4X has anti-cancer activity and prevents oncogenesis in BALBc mice[J].Cancer Medicine,2016,5(9):2 427-2 441.
[38] ALONSO E N,FERRONATO M J,GANDINI N A,et al.Antitumoral effects of D-fraction from Grifola frondosa(Maitake)mushroom in breast cancer[J].Nutrition & Cancer,2017,69(1):29-43.
[39] MAO G H,REN Y,FENG W W,et al.Antitumor and immunomodulatory activity of a water-soluble polysaccharide from Grifola frondosa[J].Carbohydrate Polymers,2015,134:406-412.
[40] 闫训友,吴智艳.灰树花生理活性物质的研究进展[J].食用菌学报,2006(6):1-2.YAN X Y,WU Z Y.Research progress of physiological active substances in Grifola frondosa[J].Edible Fungi,2006(6):1-2.
[41] 李小定,吴谋成,曾晓波,等.灰树花多糖PGF-1对荷瘤小鼠免疫功能的影响[J].华中农业大学学报,2002,21(3):261-263.LI X D,WU M C,ZENG X B,et al.Effect of polysaccharide of Grifola frondosa(PGF-1)on immunological function in tumor-bearing mice[J].Journal of Huazhong Agricultural University,2002,21(3):261-263.
[42] LI Q,ZHANG F M,CHEN G Y,et al.Purifification,characterization and immunomodulatory activity of a novel polysaccharide from Grifola frondosa[J].International Journal of Biological Macromolecules,2018,111:1 293-1 303.
[43] YAN X,YANG C F,LIN G P,et al.Antidiabetic potential of green seaweed Enteromorpha prolifera flavonoids regulating insulin signaling pathway and gut microbiota in type 2 diabetic mice[J].Journal of Food Science,2019,84(1):165-173.
[44] CHEN Y Q,LIU D,WANG D Y,et al.Hypoglycemic activity and gut microbiota regulation of a novel polysaccharide from Grifola frondosa in type 2 diabetic mice[J].Food and Chemical Toxicology,2019,126:295-302.
[45] 雷红,王毅,蔡亮亮,等.灰树花子实体多糖的降血糖活性和对α-葡萄糖苷酶活性的影响[J].食品科学,2010,31(11):263-267.LEI H,WANG Y,CAI L L,et al.Hypoglycemic activity of polysaccharides from fruit body of Grifola frondosa and its effect on α-glucosidase activity[J].Food Science,2010,31(11):263-267.
[46] PAN Y Y,ZENG F,GUO W L,et al.Effect of Grifola frondosa 95% ethanol extract on lipid metabolism and gut microbiota composition in high-fat diet-fed rats[J].Food & Function,2018,9(12):6 268-6 278.
[47] 项哨,朱圣禾,朱永平,等.灰树花多糖在小鼠体内抗病毒作用的研究[J].浙江医科大学学报,1995(5):203-205.XIANG S,ZHU S H,ZHU Y P,et al.Study on antiviral activity of grifolon polysaccharide in mice in vivo[J].Journal of Zhejiang Medical University,1995(5):203-205.
[48] NANBA H,KODAMA N,SCHAR D,et al.Effects of Maitake(Grifola frondosa)glucan in HIV-infected patients[J].Mycoscience,2000,41:293-295.
[49] 高路营.灰树花多糖对EV71病毒抑制作用的研究[D].南京:南京大学,2015:24-27.GAO L Y.Functional polysaccharide of Grifola frondosa inhibit the replication and viability of enterovirus 71[D].Nanjing:Nanjing University,2015:24-27.
[50] ZHAO C,GAO L,WANG C,et al.Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71[J].Carbohydrate Polymers,2016,144:382-389.
[51] MENG M,ZHANG R,HAN R,et al.The polysaccharides from the Grifola frondosa fruiting body prevent lipopolysaccharide/D-galactosamine-induced acute liver injury via the miR-122-Nrf2/ARE pathways[J].Food & Function,2021,12(5):1 973-1 982.
[52] COTILLARD A,KENNEDY S P,KONGL C,et al.Dietary intervention impact on gut microbial gene richness[J].Nature,2013,500:585-588.
[53] GUO W L,DENG J C,PAN Y Y,et al.Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin[J].International Journal of Biological Macromolecules,2020,153:1 231-1 240.
[54] KLAUS A,KOZARSKI M,VUNDUK J,et al.Biological potential of extracts of the wild edible basidiomycete mushroom Grifola frondosa[J].Food Research International,2015,67:272-283.
[55] ZHANG C,GAO Z,HU C,et al.Antioxidant,antibacterial and anti-aging activities of intracellular zinc polysaccharides from Grifola frondosa SH-05.[J].International Journal of Biological Macromolecules,2017,95:778-787.
[56] 汪维云.灰树花多糖的抗辐射作用研究[J].安徽农业大学学报,2003(2):210-212.WANG W Y.Anti-radiation effect of Grifola frondosa polysaccharide[J].Journal of Anhui Agricultural College,2003(2):210-212.

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