Study on the anti-fatigue activity of chickpea peptide

Authors

DONG Jing-ru, Guangxi University for Nationalities, Nanning, Guangxi 530006, China; State Ethnic Affairs Commission Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi University for Nationalities, Nanning, Guangxi 530006, China; Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Nanning, Guangxi 530006, China; Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Nanning, Guangxi 530006, China
MO Jun-ming, Guangxi University for Nationalities, Nanning, Guangxi 530006, China; State Ethnic Affairs Commission Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi University for Nationalities, Nanning, Guangxi 530006, China; Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Nanning, Guangxi 530006, China; Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Nanning, Guangxi 530006, ChinaFollow
WANG Sheng, Nanning Pangbo Biological Engineering Co., Ltd., Nanning, Guangxi 530031, China

Corresponding Author(s)

莫君明（1983—），男，广西民族大学副教授，博士。E-mail：moandli@163.com

Abstract

Objective: This study aimed to investigate the anti-fatigue activity of chickpea polypeptide and its anti-fatigue mechanism. Methods: Weight-bearing swimming test, fatigue-related biochemical index analysis and immune activity determination were analyzed in mice. Results: In the weight-bearing swimming test, the swimming time of the chickpea polypeptide-fed group was significantly longer than that of the control group (P<0.01). The test results of biochemical indicators showed that chickpea polypeptide significantly reduced the levels of urea nitrogen and blood lactic acid in the blood of mice, and also significantly increased the contents of liver glycogen, muscle glycogen and insulin (P<0.01). Chickpea polypeptide also significantly improved the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and lactate dehydrogenase (LDH). In addition, chickpea polypeptide supplementation improved the immunity by increasing phagocyte activity, stimulating sIgA secretion and reducing proinflammatory cytokines in mice. Conclusion: Chickpea polypeptide has a strong anti-fatigue effect on mice.

Publication Date

4-25-2023

First Page

142

Last Page

146

DOI

10.13652/j.spjx.1003.5788.2022.80489

Recommended Citation

Jing-ru, DONG; Jun-ming, MO; and Sheng, WANG (2023) "Study on the anti-fatigue activity of chickpea peptide," Food and Machinery: Vol. 39: Iss. 3, Article 24.
DOI: 10.13652/j.spjx.1003.5788.2022.80489
Available at: https://www.ifoodmm.cn/journal/vol39/iss3/24

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