•  
  •  
 

Authors

ZHOU Meng-jiao, Mianyang Key Laboratory for the Development and Utilization of Traditional Chinese Medicine Resources, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China; Laboratory of Research Development and Utilization on Traditional Chinese Medicine Resources in Northwest Sichuan, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China
HE Xin-zhu, Mianyang Key Laboratory for the Development and Utilization of Traditional Chinese Medicine Resources, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China; Laboratory of Research Development and Utilization on Traditional Chinese Medicine Resources in Northwest Sichuan, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China; School of Materials and Chemistry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China
LI Chao-jun, Mianyang Key Laboratory for the Development and Utilization of Traditional Chinese Medicine Resources, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China; Laboratory of Research Development and Utilization on Traditional Chinese Medicine Resources in Northwest Sichuan, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China; School of Materials and Chemistry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China
LIANG Xiao-feng, Mianyang Key Laboratory for the Development and Utilization of Traditional Chinese Medicine Resources, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China; Laboratory of Research Development and Utilization on Traditional Chinese Medicine Resources in Northwest Sichuan, Sichuan College of Traditional Chinese Medicine, Mianyang, Sichuan 621010, China; School of Materials and Chemistry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, ChinaFollow

Corresponding Author(s)

梁晓峰(1975—),男,四川中医药高等专科学校教授,博士。E-mail:XFLiang@Swust.edu.cn

Abstract

Objective: This study aimed to investigate the antioxidation and synergistic effect of flavonoid extract of Zanthoxylum armatum DC. Methods: DPPH radical and ABTS radical scavenging methods were used to evaluate the antioxidant activity of flavonoids extract from Z. armatum, and the synergies of flavonoids extract with vitamin C and rutin complex were studied by adding method. Results: The semi-inhibitory concentrations of DPPH free radical and ABTS free radical IC50 were 0.03 and 0.062 mg/mL, respectively, showing strong antioxidant activity. The antioxidant activity of the complex composed of flavonoid extract and vitamin C or rutin was high, and the antioxidant activity of the complex composed of vitamin C and flavonoid extract was higher than that of rutin and flavonoid extract when the ratio was 1∶1. Conclusion: The flavonoids of Z. armatum have strong antioxidant activity, and their complex composed of vitamin C and rutin can improve the scavenging capacity of DPPH free radical and ABTS free radicals. The extracted flavonoids have antioxidant synergistic effect, and can be used as a potential source of natural antioxidants.

Publication Date

6-9-2023

First Page

139

Last Page

143

DOI

10.13652/j.spjx.1003.5788.2022.80809

References

[1] 陈艳, 饶朝龙, 李美凤, 等. 藤椒的活性成分与开发应用研究[J]. 中国调味品, 2018, 43(3): 163-166. CHEN Y, RAO C L, LI M F, et al. Research on the active ingredients and development and application of Zanthoxylum armatum DC[J]. China Condiment, 2018, 43(3): 163-166.
[2] 赵容, 张萌萌, 陈茜, 等. 基于DPPH、ABTS法的竹叶花椒抗氧化谱效关系研究[J]. 中国调味品, 2020, 45(5): 7-12. ZHAO R, ZHANG M M, CHEN X, et al. Research on spectra-effect relationship of antioxidant activity of Zanthoxylum armatum DC.based on DPPH and ABTS methods[J]. China Condiment, 2020, 45(5): 7-12.
[3] BHATT V, SHARMA S, KUMAR N, et al. Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS[J]. Journal of Pharmaceutical and Biomedical Analysis, 2017, 132: 46-55.
[4] 周孟焦, 陈凯, 史芳芳, 等. 微波辅助法从藤椒果皮中提取黄酮的工艺研究[J]. 农产品加工, 2020(15): 23-25. ZHOU M J, CHEN K, SHI F F, et al. Experimental study on microwave-assisted extraction of flavonoids from the pericarp of Zanthoxylum armatum DC[J]. Farm Products Processing, 2020(15): 23-25.
[5] RHMAN M A, DEVNARAIN N, KHAN R, et al. Synergism potentiates oxidative antiproliferative effects of naringenin and quercetin in MCF-7 breast cancer cells[J]. Nutrients, 2022, 14(16): 3 437.
[6] MYINT K Z, ZHOU Z Y, XIA Y M, et al. Stevia polyphenols: A stable antioxidant that presents a synergistic effect with vitamin C[J]. Journal of Food Processing and Preservation, 2021, 45(4): e15317.
[7] LI N, LIU J X, YANG L, et al. Synergistic effect of antioxidant systems enhance cadmium phytoextraction and translocation in Amaranthus hypochondriacus under rutin application[J]. South African Journal of Botany, 2022, 149: 582-590.
[8] 夏陈, 向卓亚, 朱永清, 等. 不同品种青稞中总多酚、总黄酮含量及抗氧化性比较[J]. 食品与机械, 2020, 36(6): 162-165. CHEN X, XIANG Z Y, ZHU Y Q, et al. Comparative analysis of total flavonoids, total polyphenols and antioxidant properties in different varieties of Hulless barley[J]. Food & Machinery, 2020, 36(6): 162-165.
[9] 李娜, 燕平梅, 乔宏萍, 等. 南瓜果实黄酮提取工艺条件优化及其抗氧化性研究[J]. 中国调味品, 2020, 45(8): 24-30. LI N, YAN P M, QIAO H P, et al.Study on optimization of extraction technology conditions for flavonoids from pumpkin fruits and their antioxidant activity[J]. China Condiment, 2020, 45(8): 24-30.
[10] 周孟焦. 竹叶花椒中黄酮类物质提取及抗氧化性研究[D]. 绵阳: 西南科技大学, 2021: 32-33. ZHOU M J. Study on extraction of flavonoids from Zanthoxylum armatum DC and its antioxidant activity[D]. Mianyang: Southwest University of Science and Technology, 2021: 32-33.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.