Optimization of ginseng ratio and semen ziziphi spinosae antioxidant activity based on the combination of entropy-weight method and grey-correlation degree method

Authors

XIAO Feng-qin, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China
WANG Xin, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China
LIU Hui, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China
DONG Hong-ying, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China
ZHOU Wen-wen, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China
XUE Zhi-jia, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China
LI Guang-zhe, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China
YAN Ming-ming, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China;Jinlin Provincial Science and Technology Innovation Center of Health Food of Chinese Medicine, Changchun, Jilin 130117, ChinaFollow

Corresponding Author(s)

严铭铭（1968—），女，长春中医药大学教授，博士生导师，博士。E-mail：yanmm595@yahoo.com.cn李光哲（1972—），男，长春中医药大学教授，博士。E-mail：ligz@nenu.edu.con

Abstract

Objective： This study aimed to develop relevant health products with ginseng and semen ziziphi spinosae as raw materials. Methods: HPLC and UV spectrophotometer were used to study the chemical components of different compatibility ratios of ginseng and semen ziziphi spinosae. The antioxidant activity in vitro of ginseng and semen ziziphi spinosae with different compatibility ratios was analyzed by DPPH free radical, ABTS⁺free radical, hydroxyl free radical and superoxide anion free radical scavenging rate. Moreover, the grey relational degree method was used, and entropy weight method was used as the discrimination coefficient for statistical analysis, combined with the characteristics of comprehensive evaluation to optimize the compatibility ratio. Results: The correlation analysis showed that the antioxidant activity of ginseng-semen ziziphi spinosae and the content of total phenolic acid, Jujuboside A and spinosin were significantly correlated; and the chemical content determination results showed that the total phenolic acid, Jujuboside A and spinosin content of ginseng- semen ziziphi spinosae (1∶1) were higher than the other ratio. The results showed that its antioxidant activity was stronger than other ratios. Furthermore, the pharmacodynamic bases of its antioxidant activity were total phenolic acid, Jujuboside A, and spinosin. Conclusion: The optimal ratio of antioxidant activity of ginseng and semen ziziphi spinosae is m _ginseng∶m_{semen ziziphi spinosae} at 1∶1.

Publication Date

10-20-2023

First Page

173

Last Page

179

DOI

10.13652/j.spjx.1003.5788.2022.80805

Recommended Citation

Feng-qin, XIAO; Xin, WANG; Hui, LIU; Hong-ying, DONG; Wen-wen, ZHOU; Zhi-jia, XUE; Guang-zhe, LI; and Ming-ming, YAN (2023) "Optimization of ginseng ratio and semen ziziphi spinosae antioxidant activity based on the combination of entropy-weight method and grey-correlation degree method," Food and Machinery: Vol. 39: Iss. 6, Article 27.
DOI: 10.13652/j.spjx.1003.5788.2022.80805
Available at: https://www.ifoodmm.cn/journal/vol39/iss6/27

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