Abstract
Objective: A simultaneous determination method was established for detecting 19 kinds of quinolones and sulfonamides in aquatic products simultaneously, by using QuEChERS combined with UPLC-MS/MS. Methods: Samples were extracted with 1.0% formic acid acetonitrile solution, ultrasonic for 1 min, and purified by QuEChERS multi-function needle filter. The sample purification and filtering were performed simultaneously. The Mass spectrometry was conducted by using positive (ESI+) electrospray ionization and multi-reactions monitoring (MRM) models, with external standard method. Results: The detection limit of 19 kinds of sulfonamides and quinolones is from 0.5 to 1.0 μg/kg. Compared with the national standard method, the detection sensitivity is improved. The added recoveries were from 81.0% to 113.0%, and the relative standard deviation (RSD) were from 0.2% to 11.7%. Conclusion: This method assisted ultrasonic extraction and QuEChERS, enhanced the efficiency of measuring quinolones and sulfonamides in aquatic products. It is a simple, rapid, sensitivity, accurate method, which provides an efficient technical means for daily monitoring of sulfonamides and quinolones in large quantities of aquatic product samples.
Publication Date
10-20-2023
First Page
40
Last Page
47,240
DOI
10.13652/j.spjx.1003.5788.2022.81147
Recommended Citation
Juan, SUN; Jing, YANG; Chun-hui, ZHAO; Yuan, SHEN; Ying, LI; and Fang, FANG
(2023)
"Modified QuEChERS method combined with ultra-high performance liquid chromatography-tandem mass spectrometry for simultaneous determination of 19 quinolones and sulfonamides in aquatic products,"
Food and Machinery: Vol. 39:
Iss.
7, Article 6.
DOI: 10.13652/j.spjx.1003.5788.2022.81147
Available at:
https://www.ifoodmm.cn/journal/vol39/iss7/6
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