Abstract
Pectin,known for its excellent physical properties,is widely utilized across various fields,including food,medicine and cosmetics.Polyphenols,although highly bioactivity,often suffer from poor solubility and low bioavailability.Grafting polyphenols onto pectin enhances the functional value of both pectin and polyphenols.The synthesis method of polyphenols -pectin complex (non-covalently bound and covalently bound ),structural characterization (ultraviolet -visible spectroscopy,Fourier transform infrared spectroscopy,nuclear magnetic resonance hydrogen spectroscopy,scanning electron microscope,X-ray diffraction,differential scanning calorimetry,and thermogravimetric analysis ),biological activity (antioxidant activity,antibacterial activity,and antitumor activity ).Lastly,the diverse applications of polyphenol -pectin complexes in multiple fields and their potential for future development are explored.
Publication Date
2-18-2025
First Page
219
Last Page
228
DOI
10.13652/j.spjx.1003.5788.2024.80222
Recommended Citation
Peijun, LI; Xingye, CAO; Runsheng, XIE; Hui, TANG; and Ruimin, ZHONG
(2025)
"Progress in the synthesis , characterization , and biological activity of polyphenol pectin complexes,"
Food and Machinery: Vol. 40:
Iss.
11, Article 30.
DOI: 10.13652/j.spjx.1003.5788.2024.80222
Available at:
https://www.ifoodmm.cn/journal/vol40/iss11/30
References
[1] GAO H X,HE Z,SUN Q,et al.A functional polysaccharide |film forming by pectin,chitosan,and tea polyphenols [J].Carbohydrate Polymers,2019,215:1-7.
[2] CIRIMINNA R,FIDALGO A,MENEGUZZO F,et al.Pectin:a long-neglected broad-spectrum antibacterial [J].Chem Med Chem,2020,15(23):2 228-2 235.
[3] NOREEN A,NAZLI Z I H,AKRAM J,et al.Pectins functionalized biomaterials;a new viable approach for biomedical applications:a review [J].International Journal of Biological Macromolecules,2017,101:254-272.
[4] WILLATS W G T,MCCARTNEY L,MACKIE W,et al.Pectin:cell biology and prospects for functional analysis [J].Plant Molecular Biology,2001,47(1/2):9-27.
[5] MA X B,CHI C D,PU Y F,et al.Conjugation of soy protein isolate (SPI) with pectin:effects of structural modification of the grafting polysaccharide [J].Food Chemistry,2022,387:132876.
[6] BASAK S,ANNAPURE U S.Trends in "green" and novel methods of pectin modification:a review [J].Carbohydrate Polymers,2022,278:118967.
[7] 张迪,付美玲,费丛璇,等.果胶的提取、生理功能及应用研究进展 [J].食品与机械,2024,40(3):233-240.ZHANG D,FU M L,FEI C X,et al.Research progress on preparation and characteristics of polysaccharide plant protein complex [J].Food & Machinery,2024,40(3):233-240.
[8] ZHANG W T,SUN J,LI Q,et al.Free radical-mediated grafting of natural polysaccharides such as chitosan,starch,inulin,and pectin with some polyphenols:synthesis,structural characterization,bioactivities,and applications:a review [J].Foods,2023,12(19):3 688.
[9] XIE F,YANG W L,XING M X,et al.Natural polyphenols-gut microbiota interactions and effects on glycolipid metabolism via polyphenols-gut-brain axis:a state-of-the-art review [J].Trends in Food Science & Technology,2023,140:104171.
[10] WANG Y,XIE Y,WANG A D,et al.Insights into interactions between food polyphenols and proteins:an updated overview[J].Journal of Food Processing and Preservation,2022,46(5):e16597.
[11] SINGLA R K,DUBEY A K,GARG A,et al.Natural polyphenols:chemical classification,definition of classes,subcategories,and structures [J].Journal of Aoac International,2019,102(5):1 397-1 400.
[12] ZEKRUMAH M,BEGUA P,RAZAK A,et al.Role of dietary polyphenols in non-communicable chronic disease prevention,and interactions in food systems:an overview [J].Nutrition,2023,112:112034.
[13] XU Y A,WEI Z H,XUE C H,et al.Covalent modification of zein with polyphenols:a feasible strategy to improve antioxidant activity and solubility [J].Journal of Food Science,2022,87(7):2 965-2 979.[14] KARAKI N,ALJAWISH A,MUNIGLIA L,et al.Physicochemical characterization of pectin grafted with exogenous phenols [J].Food Hydrocolloids,2016,60:486-493.
[15] RAGHAV N,VASHISTH C,MOR N,et al.Recent advances in cellulose,pectin,carrageenan and alginate-based oral drug delivery systems [J].International Journal of Biological Macromolecules,2023,244:125357.
[16] 王丽颖,李福香,杨雅轩,等.多糖与多酚相互作用机制及其对多酚特性的影响研究进展 [J].食品科学,2017,38(11):276-282.WANG L Y,LI F X,YANG Y X,et al.Progress in the mechanism of interaction between polysaccharides and polyphenols and their influence on their properties [J].Food Science,2017,38(11):276-282.
[17] ZHANG X,LI M,ZHAO W,et al.Hawthorn juice simulation system for pectin and polyphenol adsorption behavior:kinetic modeling properties and identification of the interaction mechanism [J].Foods,2022,11(18):2 813.
[18] MAMET T,GE Z Z,ZHANG Y,et al.Interactions between highly galloylated persimmon tannins and pectins [J].International Journal of Biological Macromolecules,2018,106:410-417.
[19] LIU X,RENARD C M G C,ROLLAND-SABATÉ A,et al.Exploring interactions between pectins and procyanidins:structure-function relationships [J].Food Hydrocolloids,2021,113:106498.
[20] FU W,LI S,HELMICK H,et al.Complexation with polysaccharides enhances the stability of isolated anthocyanins[J].Foods,2023,12(9):1 846.
[21] MUNDLIA J,AHUJA M,KUMAR P,et al.Pectin-curcumin composite:synthesis,molecular modeling and cytotoxicity [J].Polymer Bulletin,2018,76(6):3 153-3 173.
[22] MUNDLIA J,AHUJA M,KUMAR P,et al.Improved antioxidant,antimicrobial and anticancer activity of naringenin on conjugation with pectin [J].Biotech,2019,9(8):312.
[23] AHN S,HALAKE K,LEE J.Antioxidant and ion-induced gelation functions of pectins enabled by polyphenol conjugation [J].International Journal of Biological Macromolecules,2017,101:776-782.
[24] KARAKI N,ALJAWISH A,MUNIGLIA L,et al.Functionalization of pectin with laccase-mediated oxidation products of ferulic acid [J].Enzyme and Microbial Technology,2017,104:1-8.
[25] ZHANG G,HUANG B,ZHENG C,et al.Investigation of a lipase-catalyzed reaction between pectin and salicylic acid and its isomers and evaluation of the emulsifying properties,antioxidant activities,and antibacterial activities of the corresponding products [J].Journal of Agricultural and Food Chemistry,2021,69(4):1 234-1 241.
[26] LIU J,WANG T,HUANG B,et al.Pectin modified with phenolic acids:evaluation of their emulsification properties,antioxidation activities,and antibacterial activities [J].International Journal of Biological Macromolecules,2021,174:485-493.
[27] HUANG X,HONG M,WANG L,et al.Bioadhesive and antibacterial edible coating of EGCG-grafted pectin for improving the quality of grapes during storage [J].Food Hydrocolloids,2023,136:108255.
[28] 杨鹄隽.柑橘果胶与酚酸自由基接枝共聚物结构表征及生物活性研究 [D].黑龙江:八一农垦大学,2022:1-41.YANG H J.Structural characterization and biological activity of citrus pectin graft copolymer with phenolic acid radical [D].Heilongjiang:Bayi Agricultural Reclamation University,2022:1-41.
[29] WANG C,CAI W D,YAO J,et al.Conjugation of ferulic acid onto pectin affected the physicochemical,functional and antioxidant properties [J].Journal of the Science of Food and Agriculture,2020,100(15):5 352-5 362.
[30] REN Y,YU D,WU J,et al.Preparation and physicochemical properties characterization of hesperetin-grafted pectin conjugate [J].International Journal of Biological Macromolecules,2023,243:124887.
[31] AKRETCHE H,PIERRE G,MOUSSAOUI R,et al.Valorization of olive mill wastewater for the development of biobased polymer films with antioxidant properties using eco-friendly processes [J].Green Chemistry,2019,21(11):3 065-3 073.
[32] SHI Z J,YANG H Y,JIAO J Y,et al.Effects of graft copolymer of chitosan and salicylic acid on reducing rot of postharvest fruit and retarding cell wall degradation in grapefruit during storage [J].Food Chemistry,2019,283:92-100.
[33] CURCIO M,PUOCI F,IEMMA F,et al.Covalent insertion of antioxidant molecules on chitosan by a free radical grafting procedure [J].Journal of Agricultural and Food Chemistry,2009,57(13):5 933-5 938.
[34] LIU J,LU J F,KAN J,et al.Synthesis,characterization and in vitro anti-diabetic activity of catechin grafted inulin [J].International Journal of Biological Macromolecules,2014,64:76-83.
[35] WORANUCH S,YOKSAN R.Preparation,characterization and antioxidant property of water-soluble ferulic acid grafted chitosan [J].Carbohydrate Polymers,2013,96(2):495-502.
[36] XU C,GUAN S,XU J,et al.Preparation,characterization and antioxidant activity of protocatechuic acid grafted carboxymethyl chitosan and its hydrogel [J].Carbohydr Polym,2021,252:117210.
[37] PAINI M,ALIAKBARIAN B,CASAZZA A A,et al.Chitosan/dextran multilayer microcapsules for polyphenol co-delivery[J].Materials Science & Engineering C-Materials for Biological Applications,2015,46:374-380.
[38] LIU J,PU H,LIU S,et al.Synthesis,characterization,bioactivity and potential application of phenolic acid grafted chitosan:a review [J].Carbohydr Polym,2017,174:999-1 017.
[39] YONG H M,BAI R Y,BI F Y,et al.Synthesis,characterization,antioxidant and antimicrobial activities of starch aldehyde-quercetin conjugate [J].International Journal of Biological Macromolecules,2020,156:462-470.
[40] ZHU F.Polysaccharide based films and coatings for food packaging:effect of added polyphenols [J].Food Chemistry,2021,359:129871.
[41] WATRELOT A A,SCHULZ D L,KENNEDY J A.Wine polysaccharides influence tannin-protein interactions [J].Food Hydrocolloids,2017,63:571-579.
[42] ACEVEDO-FANI A,SOLIVA-FORTUNY R,MARTÍN-BELLOSO O.Nanostructured emulsions and nanolaminates for delivery of active ingredients:improving food safety and functionality [J].Trends in Food Science & Technology,2017,60:12-22.