Determination of ethylenediaminetetraacetic acid and nitrilotriacetic acid in water

Authors

WANG Xueting, CAIQ 〔Shanghai〕 Testing Technology Co., Ltd., Shanghai 201206, ChinaFollow
ZHENG Bin, CAIQ 〔Shanghai〕 Testing Technology Co., Ltd., Shanghai 201206, China

Abstract

Objective: A high performance liquid chromatography method was developed to determine EDTA and NTA in water. Methods: The samples were derivatized with ferric chloride, used methanol and a 0.2 mmol/L tetrabutylammonium bromide phosphate buffer solution (pH 2.5) as the mobile phase, separated on a Thermo-C₁₈ (4.6 mm×250 mm) column after gradient elution, detected by HPLC with a diode array detector, and used external standard method for quantitation. Results: The content of EDTA and NTA showed a good linear relationship in the range of 0.1～2.0 mg/L, the correlation coefficients were 0.999 5 and 0.999 2 respectively; The limits of detection were 0.05 mg/L and limits of quantification were 0.1 mg/L; The average recoveries were 93.5%～111.4%; And the relative standard deviations (RSD) were 3.63%～7.39%. Conclusion: This method was convenient, repeatable, sensitive, and practical for the detection of EDTA and NTA.

Publication Date

3-27-2024

First Page

74

Last Page

77,232

DOI

10.13652/j.spjx.1003.5788.2023.80355

Recommended Citation

Xueting, WANG and Bin, ZHENG (2024) "Determination of ethylenediaminetetraacetic acid and nitrilotriacetic acid in water," Food and Machinery: Vol. 40: Iss. 2, Article 11.
DOI: 10.13652/j.spjx.1003.5788.2023.80355
Available at: https://www.ifoodmm.cn/journal/vol40/iss2/11

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