Research progress on the mechanism of food-derived antihypertensive peptides

Authors

WANG Baobei, Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou, Fujian 362000, China;Key Laboratory of Inshore Resources and Biotechnology Fujian Province University, Quanzhou, Fujian 362000, China
ZHANG Hui, Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou, Fujian 362000, China;College of Food Science, Fujian Agriculture University, Fuzhou, Fujian 350002, China
LIU Yusong, Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou, Fujian 362000, China
CHEN Hongbin, Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou, Fujian 362000, China;Key Laboratory of Inshore Resources and Biotechnology Fujian Province University, Quanzhou, Fujian 362000, China
GUO Fengxian, Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou, Fujian 362000, China;Key Laboratory of Inshore Resources and Biotechnology Fujian Province University, Quanzhou, Fujian 362000, China
ZHENG Zongping, Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou, Fujian 362000, China;Key Laboratory of Inshore Resources and Biotechnology Fujian Province University, Quanzhou, Fujian 362000, ChinaFollow

Corresponding Author(s)

郑宗平（1976—），男，泉州师范学院教授，博士。E-mail：zzpsea@qztc.edu.cn

Abstract

In this review, several mechanisms of antihypertensive peptides derived from food and its by-products were summarized. Mechanisms based on the RAAS system such as ACE/Ang Ⅱ/AT1R signaling pathways and ACE2/Ang (1-7)/MasR signaling pathways were included. Mechanisms targeting at KNOS system including PI3K/Akt/eNOS signaling pathway, PPAR-γ/caspase3/MAPK/eNOS signaling pathway and L-type Ca²⁺ channel were also discussed. In addition, the pathways of reducing blood pressure by inhibiting endothelin-converting enzyme (ECE) activity discovered in recent years were also introduced.

Publication Date

4-30-2024

First Page

217

Last Page

224

DOI

10.13652/j.spjx.1003.5788.2023.80842

Recommended Citation

Baobei, WANG; Hui, ZHANG; Yusong, LIU; Hongbin, CHEN; Fengxian, GUO; and Zongping, ZHENG (2024) "Research progress on the mechanism of food-derived antihypertensive peptides," Food and Machinery: Vol. 40: Iss. 3, Article 30.
DOI: 10.13652/j.spjx.1003.5788.2023.80842
Available at: https://www.ifoodmm.cn/journal/vol40/iss3/30

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